Comorbidity polypharmacy score and its clinical utility: A pragmatic practitioner′s perspective

Modern medical management of comorbid conditions has resulted in escalating use of multiple medications and the emergence of the twin phenomena of multimorbidity and polypharmacy. Current understanding of how the polypharmacy in conjunction with multimorbidity influences trauma outcomes is limited,...

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Main Authors: Stanislaw P Stawicki, Sarathi Kalra, Christian Jones, Carla F Justiniano, Thomas J Papadimos, Sagar C Galwankar, Scott M Pappada, John J Feeney, David C Evans
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Journal of Emergencies, Trauma and Shock
Subjects:
Online Access:http://www.onlinejets.org/article.asp?issn=0974-2700;year=2015;volume=8;issue=4;spage=224;epage=231;aulast=Stawicki
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author Stanislaw P Stawicki
Sarathi Kalra
Christian Jones
Carla F Justiniano
Thomas J Papadimos
Sagar C Galwankar
Scott M Pappada
John J Feeney
David C Evans
author_facet Stanislaw P Stawicki
Sarathi Kalra
Christian Jones
Carla F Justiniano
Thomas J Papadimos
Sagar C Galwankar
Scott M Pappada
John J Feeney
David C Evans
author_sort Stanislaw P Stawicki
collection DOAJ
description Modern medical management of comorbid conditions has resulted in escalating use of multiple medications and the emergence of the twin phenomena of multimorbidity and polypharmacy. Current understanding of how the polypharmacy in conjunction with multimorbidity influences trauma outcomes is limited, although it is known that trauma patients are at increased risk for medication-related adverse events. The comorbidity-polypharmacy score (CPS) is a simple clinical tool that quantifies the overall severity of comorbidities using the polypharmacy as a surrogate for the "intensity" of treatment necessary to adequately control chronic medical conditions. Easy to calculate, CPS is derived by counting all known pre-injury comorbid conditions and medications. CPS has been independently associated with mortality, increased risk for complications, lower functional outcomes, readmissions, and longer hospital stays. In addition, CPS may help identify older trauma patients at risk of post-emergency department undertriage. The goal of this article was to review and refine the rationale for CPS and to provide an evidence-based outline of its potential clinical applications.
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spelling doaj.art-d95f5c2e3dce4788b4ce879c7f56be822022-12-21T22:42:39ZengWolters Kluwer Medknow PublicationsJournal of Emergencies, Trauma and Shock0974-27002015-01-018422423110.4103/0974-2700.161658Comorbidity polypharmacy score and its clinical utility: A pragmatic practitioner′s perspectiveStanislaw P StawickiSarathi KalraChristian JonesCarla F JustinianoThomas J PapadimosSagar C GalwankarScott M PappadaJohn J FeeneyDavid C EvansModern medical management of comorbid conditions has resulted in escalating use of multiple medications and the emergence of the twin phenomena of multimorbidity and polypharmacy. Current understanding of how the polypharmacy in conjunction with multimorbidity influences trauma outcomes is limited, although it is known that trauma patients are at increased risk for medication-related adverse events. The comorbidity-polypharmacy score (CPS) is a simple clinical tool that quantifies the overall severity of comorbidities using the polypharmacy as a surrogate for the "intensity" of treatment necessary to adequately control chronic medical conditions. Easy to calculate, CPS is derived by counting all known pre-injury comorbid conditions and medications. CPS has been independently associated with mortality, increased risk for complications, lower functional outcomes, readmissions, and longer hospital stays. In addition, CPS may help identify older trauma patients at risk of post-emergency department undertriage. The goal of this article was to review and refine the rationale for CPS and to provide an evidence-based outline of its potential clinical applications.http://www.onlinejets.org/article.asp?issn=0974-2700;year=2015;volume=8;issue=4;spage=224;epage=231;aulast=StawickiComorbidity-polypharmacy scoreelderly trauma patientestimation of frailtymultimorbidityphysiologic agepublic healthworld demographics
spellingShingle Stanislaw P Stawicki
Sarathi Kalra
Christian Jones
Carla F Justiniano
Thomas J Papadimos
Sagar C Galwankar
Scott M Pappada
John J Feeney
David C Evans
Comorbidity polypharmacy score and its clinical utility: A pragmatic practitioner′s perspective
Journal of Emergencies, Trauma and Shock
Comorbidity-polypharmacy score
elderly trauma patient
estimation of frailty
multimorbidity
physiologic age
public health
world demographics
title Comorbidity polypharmacy score and its clinical utility: A pragmatic practitioner′s perspective
title_full Comorbidity polypharmacy score and its clinical utility: A pragmatic practitioner′s perspective
title_fullStr Comorbidity polypharmacy score and its clinical utility: A pragmatic practitioner′s perspective
title_full_unstemmed Comorbidity polypharmacy score and its clinical utility: A pragmatic practitioner′s perspective
title_short Comorbidity polypharmacy score and its clinical utility: A pragmatic practitioner′s perspective
title_sort comorbidity polypharmacy score and its clinical utility a pragmatic practitioner s perspective
topic Comorbidity-polypharmacy score
elderly trauma patient
estimation of frailty
multimorbidity
physiologic age
public health
world demographics
url http://www.onlinejets.org/article.asp?issn=0974-2700;year=2015;volume=8;issue=4;spage=224;epage=231;aulast=Stawicki
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