Intervention Effect of Non-Invasive Brain Stimulation on Cognitive Functions among People with Traumatic Brain Injury: A Systematic Review and Meta-Analysis
This systematic review and meta-analysis aggregated and examined the treatment effect of non-invasive brain stimulation (NIBS) (transcranial direct current stimulation and transcranial magnetic stimulation) on cognitive functions in people with traumatic brain injury (TBI). A systematic search was c...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-06-01
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| Series: | Brain Sciences |
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| Online Access: | https://www.mdpi.com/2076-3425/11/7/840 |
| _version_ | 1797412059862794240 |
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| author | Daniel Kwasi Ahorsu Emma Sethina Adjaottor Bess Yin Hung Lam |
| author_facet | Daniel Kwasi Ahorsu Emma Sethina Adjaottor Bess Yin Hung Lam |
| author_sort | Daniel Kwasi Ahorsu |
| collection | DOAJ |
| description | This systematic review and meta-analysis aggregated and examined the treatment effect of non-invasive brain stimulation (NIBS) (transcranial direct current stimulation and transcranial magnetic stimulation) on cognitive functions in people with traumatic brain injury (TBI). A systematic search was conducted using databases (PubMed, Web of Science, Scopus, PsycINFO, EMBASE) for studies with keywords related to non-randomized and randomized control trials of NIBS among people with TBI. Nine out of 1790 NIBS studies with 197 TBI participants (103 active vs. 94 sham) that met the inclusion and exclusion criteria of the present study were finally selected for meta-analysis using Comprehensive Meta-Analysis software (version 3). Results showed that the overall effect of NIBS on cognition in people with TBI was moderately significant (g = 0.304, 95% CI = 0.055 to 0.553) with very low heterogeneity across studies (<i>I</i><sup>2</sup> = 0.000, Tau = 0.000). Specifically, significant and marginally significant moderate effect sizes were found for cognitive sub-domains including attention, memory, and executive function. The present findings suggest that NIBS is moderately effective in improving cognitive functions among people with TBI. In particular, NIBS may be used as an alternative and/or an adjunct treatment to the traditional approach in rehabilitating cognitive functions in people with TBI. |
| first_indexed | 2024-03-09T04:56:37Z |
| format | Article |
| id | doaj.art-d96104d19569496eb962d96315ff6e57 |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-09T04:56:37Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-d96104d19569496eb962d96315ff6e572023-12-03T13:05:27ZengMDPI AGBrain Sciences2076-34252021-06-0111784010.3390/brainsci11070840Intervention Effect of Non-Invasive Brain Stimulation on Cognitive Functions among People with Traumatic Brain Injury: A Systematic Review and Meta-AnalysisDaniel Kwasi Ahorsu0Emma Sethina Adjaottor1Bess Yin Hung Lam2Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, ChinaDepartment of Behavioural Sciences, Kwame Nkrumah University of Science and Technology, Ashanti, GhanaDepartment of Psychiatry, The University of Hong Kong, Hong Kong, ChinaThis systematic review and meta-analysis aggregated and examined the treatment effect of non-invasive brain stimulation (NIBS) (transcranial direct current stimulation and transcranial magnetic stimulation) on cognitive functions in people with traumatic brain injury (TBI). A systematic search was conducted using databases (PubMed, Web of Science, Scopus, PsycINFO, EMBASE) for studies with keywords related to non-randomized and randomized control trials of NIBS among people with TBI. Nine out of 1790 NIBS studies with 197 TBI participants (103 active vs. 94 sham) that met the inclusion and exclusion criteria of the present study were finally selected for meta-analysis using Comprehensive Meta-Analysis software (version 3). Results showed that the overall effect of NIBS on cognition in people with TBI was moderately significant (g = 0.304, 95% CI = 0.055 to 0.553) with very low heterogeneity across studies (<i>I</i><sup>2</sup> = 0.000, Tau = 0.000). Specifically, significant and marginally significant moderate effect sizes were found for cognitive sub-domains including attention, memory, and executive function. The present findings suggest that NIBS is moderately effective in improving cognitive functions among people with TBI. In particular, NIBS may be used as an alternative and/or an adjunct treatment to the traditional approach in rehabilitating cognitive functions in people with TBI.https://www.mdpi.com/2076-3425/11/7/840traumatic brain injurycognitive functionstranscranial direct current stimulationtranscranial magnetic stimulationnon-invasive brain stimulation |
| spellingShingle | Daniel Kwasi Ahorsu Emma Sethina Adjaottor Bess Yin Hung Lam Intervention Effect of Non-Invasive Brain Stimulation on Cognitive Functions among People with Traumatic Brain Injury: A Systematic Review and Meta-Analysis Brain Sciences traumatic brain injury cognitive functions transcranial direct current stimulation transcranial magnetic stimulation non-invasive brain stimulation |
| title | Intervention Effect of Non-Invasive Brain Stimulation on Cognitive Functions among People with Traumatic Brain Injury: A Systematic Review and Meta-Analysis |
| title_full | Intervention Effect of Non-Invasive Brain Stimulation on Cognitive Functions among People with Traumatic Brain Injury: A Systematic Review and Meta-Analysis |
| title_fullStr | Intervention Effect of Non-Invasive Brain Stimulation on Cognitive Functions among People with Traumatic Brain Injury: A Systematic Review and Meta-Analysis |
| title_full_unstemmed | Intervention Effect of Non-Invasive Brain Stimulation on Cognitive Functions among People with Traumatic Brain Injury: A Systematic Review and Meta-Analysis |
| title_short | Intervention Effect of Non-Invasive Brain Stimulation on Cognitive Functions among People with Traumatic Brain Injury: A Systematic Review and Meta-Analysis |
| title_sort | intervention effect of non invasive brain stimulation on cognitive functions among people with traumatic brain injury a systematic review and meta analysis |
| topic | traumatic brain injury cognitive functions transcranial direct current stimulation transcranial magnetic stimulation non-invasive brain stimulation |
| url | https://www.mdpi.com/2076-3425/11/7/840 |
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