Assessing predictors of changes in protein stability upon mutation using self-consistency.

The ability to predict the effect of mutations on protein stability is important for a wide range of tasks, from protein engineering to assessing the impact of SNPs to understanding basic protein biophysics. A number of methods have been developed that make these predictions, but assessing the accur...

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Bibliographic Details
Main Authors: Grant Thiltgen, Richard A Goldstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23144695/?tool=EBI

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