A patient with typhoid fever, gastroenteritis and hepatitis E

Marked elevation of transaminases is rare in typhoid enteric fever. Co-infections with hepatitis A or E, dengue, or other pathogens should be suspected and investigated. Here we report a case of a 29-year-old Bangladesh man who presented with typhoid, hepatitis E and Giardia lamblia complicated by s...

Full description

Bibliographic Details
Main Authors: Qing Zhang, Jonathan Guo Xiang Teh, Webber Pak Wo Chan
Format: Article
Language:English
Published: SAGE Publishing 2016-03-01
Series:Proceedings of Singapore Healthcare
Online Access:https://doi.org/10.1177/2010105815615999
_version_ 1818347309181698048
author Qing Zhang
Jonathan Guo Xiang Teh
Webber Pak Wo Chan
author_facet Qing Zhang
Jonathan Guo Xiang Teh
Webber Pak Wo Chan
author_sort Qing Zhang
collection DOAJ
description Marked elevation of transaminases is rare in typhoid enteric fever. Co-infections with hepatitis A or E, dengue, or other pathogens should be suspected and investigated. Here we report a case of a 29-year-old Bangladesh man who presented with typhoid, hepatitis E and Giardia lamblia complicated by severely deranged liver enzymes. With early institution of antibiotics and active supportive treatment, the patient clinically recovered. The underlying mechanism of co-infection is still not clear. As clinicians, comprehensive workup for potential pathogens helps expedite diagnosis, especially in patients from endemic areas or patients who deteriorate rapidly. Current diagnostic methods, treatment modalities and preventive measures still need to be improved in the future.
first_indexed 2024-12-13T17:32:07Z
format Article
id doaj.art-d9642f69cf0b4753a6fd25734d515e73
institution Directory Open Access Journal
issn 2010-1058
2059-2329
language English
last_indexed 2024-12-13T17:32:07Z
publishDate 2016-03-01
publisher SAGE Publishing
record_format Article
series Proceedings of Singapore Healthcare
spelling doaj.art-d9642f69cf0b4753a6fd25734d515e732022-12-21T23:37:01ZengSAGE PublishingProceedings of Singapore Healthcare2010-10582059-23292016-03-012510.1177/2010105815615999A patient with typhoid fever, gastroenteritis and hepatitis EQing Zhang0Jonathan Guo Xiang Teh1Webber Pak Wo Chan2Department of Internal Medicine, Singapore General Hospital, SingaporeDepartment of Internal Medicine, Singapore General Hospital, SingaporeDepartment of Gastroenterology and Hepatology, Singapore General Hospital, SingaporeMarked elevation of transaminases is rare in typhoid enteric fever. Co-infections with hepatitis A or E, dengue, or other pathogens should be suspected and investigated. Here we report a case of a 29-year-old Bangladesh man who presented with typhoid, hepatitis E and Giardia lamblia complicated by severely deranged liver enzymes. With early institution of antibiotics and active supportive treatment, the patient clinically recovered. The underlying mechanism of co-infection is still not clear. As clinicians, comprehensive workup for potential pathogens helps expedite diagnosis, especially in patients from endemic areas or patients who deteriorate rapidly. Current diagnostic methods, treatment modalities and preventive measures still need to be improved in the future.https://doi.org/10.1177/2010105815615999
spellingShingle Qing Zhang
Jonathan Guo Xiang Teh
Webber Pak Wo Chan
A patient with typhoid fever, gastroenteritis and hepatitis E
Proceedings of Singapore Healthcare
title A patient with typhoid fever, gastroenteritis and hepatitis E
title_full A patient with typhoid fever, gastroenteritis and hepatitis E
title_fullStr A patient with typhoid fever, gastroenteritis and hepatitis E
title_full_unstemmed A patient with typhoid fever, gastroenteritis and hepatitis E
title_short A patient with typhoid fever, gastroenteritis and hepatitis E
title_sort patient with typhoid fever gastroenteritis and hepatitis e
url https://doi.org/10.1177/2010105815615999
work_keys_str_mv AT qingzhang apatientwithtyphoidfevergastroenteritisandhepatitise
AT jonathanguoxiangteh apatientwithtyphoidfevergastroenteritisandhepatitise
AT webberpakwochan apatientwithtyphoidfevergastroenteritisandhepatitise
AT qingzhang patientwithtyphoidfevergastroenteritisandhepatitise
AT jonathanguoxiangteh patientwithtyphoidfevergastroenteritisandhepatitise
AT webberpakwochan patientwithtyphoidfevergastroenteritisandhepatitise