N‐Acetylcysteine protects against cobalt chloride‐induced endothelial dysfunction by enhancing glucose‐6‐phosphate dehydrogenase activity

N‐Acetylcysteine protects against cobalt chloride‐induced endothelial dysfunction by enhancing glucose‐6‐phosphate dehydrogenase activity

Hypoxia‐induced endothelial dysfunction is known to be involved in the pathogenesis of several vascular diseases. However, it remains unclear whether the pentose phosphate pathway (PPP) is involved in regulating the response of endothelial cells to hypoxia. Here, we established an in vitro model by...

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Bibliographic Details
Main Authors: Chen Yang, Xiaofang Zhang, Xilin Ge, Chunmei He, Suhuan Liu, Shuyu Yang, Caoxin Huang
Format: Article
Language:English
Published: Wiley 2022-08-01
Series:FEBS Open Bio
Subjects:
endothelial cells
glucose‐6‐phosphate dehydrogenase
hypoxia
N‐Acetylcysteine
pentose phosphate pathway
Online Access:https://doi.org/10.1002/2211-5463.13449

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