Autoimmune hemolytic anemia and giant cell hepatitis: Report of three infants
Giant cell hepatitis associated with direct Coombs’ test-positive hemolytic anemia is a rare condition of childhood and the pathogenesis remains unclear. An autoimmune activation and loss of self-tolerance in these patients may be the underlying pathology related to the response of some of the patie...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Publishing House
2010-12-01
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| Series: | Turkish Journal of Hematology |
| Subjects: | |
| Online Access: | http://www.journalagent.com/z4/download_fulltext.asp?pdir=tjh&plng=eng&un=TJH-27132 |
| _version_ | 1827832162305441792 |
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| author | Şule Ünal Barış Kuşkonmaz Necati Balamtekin Gökhan Baysoy Selin Aytaç Elmas Diclehan Orhan Gülsev Kale Aysel Yüce Figen Gürakan Fatma Gümrük Mualla Çetin |
| author_facet | Şule Ünal Barış Kuşkonmaz Necati Balamtekin Gökhan Baysoy Selin Aytaç Elmas Diclehan Orhan Gülsev Kale Aysel Yüce Figen Gürakan Fatma Gümrük Mualla Çetin |
| author_sort | Şule Ünal |
| collection | DOAJ |
| description | Giant cell hepatitis associated with direct Coombs’ test-positive hemolytic anemia is a rare condition of childhood and the pathogenesis remains unclear. An autoimmune activation and loss of self-tolerance in these patients may be the underlying pathology related to the response of some of the patients to immunosuppressive treatment. Herein, we report the clinical presentation and course of three consecutive patients with this rare condition. We conclude that serum ferritin at diagnosis may be used for prediction of the outcome. |
| first_indexed | 2024-03-12T05:06:08Z |
| format | Article |
| id | doaj.art-d968035edd104aecb687a9efd1fcab46 |
| institution | Directory Open Access Journal |
| issn | 1300-7777 1308-5263 |
| language | English |
| last_indexed | 2024-03-12T05:06:08Z |
| publishDate | 2010-12-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Turkish Journal of Hematology |
| spelling | doaj.art-d968035edd104aecb687a9efd1fcab462023-09-03T08:55:46ZengGalenos Publishing HouseTurkish Journal of Hematology1300-77771308-52632010-12-012704308313Autoimmune hemolytic anemia and giant cell hepatitis: Report of three infantsŞule ÜnalBarış KuşkonmazNecati BalamtekinGökhan BaysoySelin Aytaç ElmasDiclehan OrhanGülsev KaleAysel YüceFigen GürakanFatma GümrükMualla ÇetinGiant cell hepatitis associated with direct Coombs’ test-positive hemolytic anemia is a rare condition of childhood and the pathogenesis remains unclear. An autoimmune activation and loss of self-tolerance in these patients may be the underlying pathology related to the response of some of the patients to immunosuppressive treatment. Herein, we report the clinical presentation and course of three consecutive patients with this rare condition. We conclude that serum ferritin at diagnosis may be used for prediction of the outcome.http://www.journalagent.com/z4/download_fulltext.asp?pdir=tjh&plng=eng&un=TJH-27132Giant cell hepatitisimmune hemolytic anemiadirect Coombs’ testrituximab |
| spellingShingle | Şule Ünal Barış Kuşkonmaz Necati Balamtekin Gökhan Baysoy Selin Aytaç Elmas Diclehan Orhan Gülsev Kale Aysel Yüce Figen Gürakan Fatma Gümrük Mualla Çetin Autoimmune hemolytic anemia and giant cell hepatitis: Report of three infants Turkish Journal of Hematology Giant cell hepatitis immune hemolytic anemia direct Coombs’ test rituximab |
| title | Autoimmune hemolytic anemia and giant cell hepatitis: Report of three infants |
| title_full | Autoimmune hemolytic anemia and giant cell hepatitis: Report of three infants |
| title_fullStr | Autoimmune hemolytic anemia and giant cell hepatitis: Report of three infants |
| title_full_unstemmed | Autoimmune hemolytic anemia and giant cell hepatitis: Report of three infants |
| title_short | Autoimmune hemolytic anemia and giant cell hepatitis: Report of three infants |
| title_sort | autoimmune hemolytic anemia and giant cell hepatitis report of three infants |
| topic | Giant cell hepatitis immune hemolytic anemia direct Coombs’ test rituximab |
| url | http://www.journalagent.com/z4/download_fulltext.asp?pdir=tjh&plng=eng&un=TJH-27132 |
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