Detection of chromosomal abnormalities in formalin-fixed and paraffin-embedded autopsy material from fetuses using FISH

Detection of chromosomal abnormalities in formalin-fixed and paraffin-embedded autopsy material from fetuses using FISH

Spontaneous abortions or intrauterine foetal deaths are in 60-70 percent of the cases caused by trisomy 13, 18, 21 or Turner syndrome. Fluorescence in situ hybridization (FISH) with centromere or locus specific probes for chromosome 13, 18, 21, X and Y was performed on formalin-fixed and paraffin-em...

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Bibliographic Details
Main Authors: Borgny Ytterhus, Ingeborg Engesvold, Christina Vogt Isaksen
Format: Article
Language:Danish
Published: NITO - Bioingeniørfaglig institutt 2009-02-01
Series:Bioingeniøren
Subjects:
fluorescence in situ hybridization
isolated nuclei
chromosomal abnormality
autopsy material
Online Access:https://bioingenioren.no/fag/fag-originalartikkel/deteksjon-av-kromosomavvik-i-formalinfiksert-og-parafininnstopt-autopsimateriale-fra-fostre-ved-hjelp-av-fish/

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