Pharmacokinetic analysis of acute and dietary exposure to piperonyl butoxide in the mouse

Pharmacokinetic analysis of acute and dietary exposure to piperonyl butoxide in the mouse

Piperonyl butoxide (PBO) is a popular insecticide synergist present in thousands of commercial, agricultural, and household products. PBO inhibits cytochrome P450 activity, impairing the ability of insects to detoxify insecticides. PBO was recently discovered to also inhibit Sonic hedgehog signaling...

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Bibliographic Details
Main Authors:	Alyssa E. Jenkins, Cameron O. Scarlett, Tyler G. Beames, Kenneth S. Rivera-González, Alexander A. Martin, Miranda R. Sun, Paul R. Hutson, Robert J. Lipinski
Format:	Article
Language:	English
Published:	Elsevier 2023-12-01
Series:	Toxicology Reports
Subjects:	Piperonyl butoxide Pharmacokinetics Mouse
Online Access:	http://www.sciencedirect.com/science/article/pii/S2214750023001099

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