Relationship between ATOH1 and tumor microenvironment in colon adenocarcinoma patients with different microsatellite instability status

Relationship between ATOH1 and tumor microenvironment in colon adenocarcinoma patients with different microsatellite instability status

Abstract Background Colon adenocarcinoma (COAD) is one of the major varieties of malignant tumors threatening human health today. Immune checkpoint inhibitors (ICIs) have recently begun to emerge as an effective option for the treatment of COAD patients, but not all patients can benefit from ICI tre...

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Bibliographic Details
Main Authors: Weiming Mou, Lingxuan Zhu, Tao Yang, Anqi Lin, Qiong Lyu, Linlang Guo, Zaoqu Liu, Quan Cheng, Jian Zhang, Peng Luo
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Cancer Cell International
Subjects:
Chromatin accessibility
Colon adenocarcinoma
Microsatellite instability
Tumor microenvironment
Immune checkpoint inhibitors
ATOH1
Online Access:https://doi.org/10.1186/s12935-022-02651-6

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