SAGA DUBm-mediated surveillance regulates prompt export of stress-inducible transcripts for proteostasis
Stress-inducible transcripts are quickly exported to preserve cell survival when cells are under stress. Here, the authors suggest that Sgf73p of the SAGA deubiquitylating module monitors messenger ribonucleoprotein biogenesis to regulate non-canonical export of stress-inducible transcripts.
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2019-06-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-10350-6 |
| _version_ | 1819040351228264448 |
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| author | Minhoo Kim Yoonjung Choi Harim Kim Daeyoup Lee |
| author_facet | Minhoo Kim Yoonjung Choi Harim Kim Daeyoup Lee |
| author_sort | Minhoo Kim |
| collection | DOAJ |
| description | Stress-inducible transcripts are quickly exported to preserve cell survival when cells are under stress. Here, the authors suggest that Sgf73p of the SAGA deubiquitylating module monitors messenger ribonucleoprotein biogenesis to regulate non-canonical export of stress-inducible transcripts. |
| first_indexed | 2024-12-21T09:07:43Z |
| format | Article |
| id | doaj.art-d96b862436bc4a378374a714644eafc6 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-21T09:07:43Z |
| publishDate | 2019-06-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-d96b862436bc4a378374a714644eafc62022-12-21T19:09:19ZengNature PortfolioNature Communications2041-17232019-06-0110111410.1038/s41467-019-10350-6SAGA DUBm-mediated surveillance regulates prompt export of stress-inducible transcripts for proteostasisMinhoo Kim0Yoonjung Choi1Harim Kim2Daeyoup Lee3Department of Biological Sciences, Korea Advanced Institute of Science and TechnologyDepartment of Biological Sciences, Korea Advanced Institute of Science and TechnologyDepartment of Biological Sciences, Korea Advanced Institute of Science and TechnologyDepartment of Biological Sciences, Korea Advanced Institute of Science and TechnologyStress-inducible transcripts are quickly exported to preserve cell survival when cells are under stress. Here, the authors suggest that Sgf73p of the SAGA deubiquitylating module monitors messenger ribonucleoprotein biogenesis to regulate non-canonical export of stress-inducible transcripts.https://doi.org/10.1038/s41467-019-10350-6 |
| spellingShingle | Minhoo Kim Yoonjung Choi Harim Kim Daeyoup Lee SAGA DUBm-mediated surveillance regulates prompt export of stress-inducible transcripts for proteostasis Nature Communications |
| title | SAGA DUBm-mediated surveillance regulates prompt export of stress-inducible transcripts for proteostasis |
| title_full | SAGA DUBm-mediated surveillance regulates prompt export of stress-inducible transcripts for proteostasis |
| title_fullStr | SAGA DUBm-mediated surveillance regulates prompt export of stress-inducible transcripts for proteostasis |
| title_full_unstemmed | SAGA DUBm-mediated surveillance regulates prompt export of stress-inducible transcripts for proteostasis |
| title_short | SAGA DUBm-mediated surveillance regulates prompt export of stress-inducible transcripts for proteostasis |
| title_sort | saga dubm mediated surveillance regulates prompt export of stress inducible transcripts for proteostasis |
| url | https://doi.org/10.1038/s41467-019-10350-6 |
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