Systemic inflammation decreases pain threshold in humans in vivo.

Systemic inflammation decreases pain threshold in humans in vivo.

Hyperalgesia is a well recognized hallmark of disease. Pro-inflammatory cytokines have been suggested to be mainly responsible, but human data are scarce. Changes in pain threshold during systemic inflammation evoked by human endotoxemia, were evaluated with three quantitative sensory testing method...

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Bibliographic Details
Main Authors: Moniek de Goeij, Lucas T van Eijk, Pascal Vanelderen, Oliver H Wilder-Smith, Kris C Vissers, Johannes G van der Hoeven, Matthijs Kox, Gert Jan Scheffer, Peter Pickkers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3866228?pdf=render

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