The Effectiveness of Prolonged-Release Melatonin in Primary Insomnia Patients with a Regular Sleep-Wake Cycle

Background and Objective Prolonged-release melatonin (PRM) might effectively increase patient satisfaction when administered to individuals older than 55 years old with primary insomnia who were not satisfied with their sleep even after their sleep-wake cycle schedule was set. We investigated patien...

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Main Authors: Seockhoon Chung, Soyoung Youn, Boram Park, Suyeon Lee, Changnam Kim
Format: Article
Language:English
Published: Korean Society of Sleep Medicine 2016-06-01
Series:Sleep Medicine Research
Subjects:
Online Access:http://www.sleepmedres.org/upload/pdf/smr-7-1-16.pdf
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author Seockhoon Chung
Soyoung Youn
Boram Park
Suyeon Lee
Changnam Kim
author_facet Seockhoon Chung
Soyoung Youn
Boram Park
Suyeon Lee
Changnam Kim
author_sort Seockhoon Chung
collection DOAJ
description Background and Objective Prolonged-release melatonin (PRM) might effectively increase patient satisfaction when administered to individuals older than 55 years old with primary insomnia who were not satisfied with their sleep even after their sleep-wake cycle schedule was set. We investigated patients’ satisfaction rate with PRM when they took it after their sleep-wake cycle was set. Methods Among 87 patients who were prescribed PRM at the sleep clinic, 44 patients with primary insomnia who complained of poor sleep quality even after adopting a set 7-hour sleep-wake schedule or taking sleeping pills 7 hours before wake-up time were selected their medical records were reviewed. We explored patients’ satisfaction rates with PRM after 3–4 weeks. Results Among the 35 subjects who completed follow-up, 23 (66%) reported an improvement in insomnia symptoms after taking PRM. Five subjects reported daytime sleepiness as treatment-emergent adverse events. Of the 25 subjects taking other sleeping pills at baseline and followed up, 11 (44%) reduced their sleeping pill dosage by at least 50%. Five subjects completely discontinued their previous sleeping pills after starting PRM. Conclusions We observed a high satisfaction rate with PRM when prescribed to patients with a regular sleep-wake cycle. We believe that the results of this study will help to optimize hypnotic prescription to insomnia patients.
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spelling doaj.art-d97f29f52f1c490eb131f28acab8d0da2022-12-22T00:57:49ZengKorean Society of Sleep MedicineSleep Medicine Research2093-91752233-88532016-06-0171162010.17241/smr.2016.0001776The Effectiveness of Prolonged-Release Melatonin in Primary Insomnia Patients with a Regular Sleep-Wake CycleSeockhoon ChungSoyoung YounBoram ParkSuyeon LeeChangnam KimBackground and Objective Prolonged-release melatonin (PRM) might effectively increase patient satisfaction when administered to individuals older than 55 years old with primary insomnia who were not satisfied with their sleep even after their sleep-wake cycle schedule was set. We investigated patients’ satisfaction rate with PRM when they took it after their sleep-wake cycle was set. Methods Among 87 patients who were prescribed PRM at the sleep clinic, 44 patients with primary insomnia who complained of poor sleep quality even after adopting a set 7-hour sleep-wake schedule or taking sleeping pills 7 hours before wake-up time were selected their medical records were reviewed. We explored patients’ satisfaction rates with PRM after 3–4 weeks. Results Among the 35 subjects who completed follow-up, 23 (66%) reported an improvement in insomnia symptoms after taking PRM. Five subjects reported daytime sleepiness as treatment-emergent adverse events. Of the 25 subjects taking other sleeping pills at baseline and followed up, 11 (44%) reduced their sleeping pill dosage by at least 50%. Five subjects completely discontinued their previous sleeping pills after starting PRM. Conclusions We observed a high satisfaction rate with PRM when prescribed to patients with a regular sleep-wake cycle. We believe that the results of this study will help to optimize hypnotic prescription to insomnia patients.http://www.sleepmedres.org/upload/pdf/smr-7-1-16.pdfInsomniaMelatoninSleepHypnotics
spellingShingle Seockhoon Chung
Soyoung Youn
Boram Park
Suyeon Lee
Changnam Kim
The Effectiveness of Prolonged-Release Melatonin in Primary Insomnia Patients with a Regular Sleep-Wake Cycle
Sleep Medicine Research
Insomnia
Melatonin
Sleep
Hypnotics
title The Effectiveness of Prolonged-Release Melatonin in Primary Insomnia Patients with a Regular Sleep-Wake Cycle
title_full The Effectiveness of Prolonged-Release Melatonin in Primary Insomnia Patients with a Regular Sleep-Wake Cycle
title_fullStr The Effectiveness of Prolonged-Release Melatonin in Primary Insomnia Patients with a Regular Sleep-Wake Cycle
title_full_unstemmed The Effectiveness of Prolonged-Release Melatonin in Primary Insomnia Patients with a Regular Sleep-Wake Cycle
title_short The Effectiveness of Prolonged-Release Melatonin in Primary Insomnia Patients with a Regular Sleep-Wake Cycle
title_sort effectiveness of prolonged release melatonin in primary insomnia patients with a regular sleep wake cycle
topic Insomnia
Melatonin
Sleep
Hypnotics
url http://www.sleepmedres.org/upload/pdf/smr-7-1-16.pdf
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