Fine-mapping and identification of candidate causal genes for tail length in the Merinolandschaf breed
Using SNP-association analysis and genetic mapping, a SNP and an insertion in and close to HOXB13 associated with short tail length is identified in Merino sheep, which may be a target for safely selecting shorter tails and improving sheep welfare.
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-09-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-03854-3 |
| _version_ | 1811273633541128192 |
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| author | Dominik Karl Lagler Elisabeth Hannemann Kim Eck Jürgen Klawatsch Doris Seichter Ingolf Russ Christian Mendel Gesine Lühken Stefan Krebs Helmut Blum Maulik Upadhyay Ivica Medugorac |
| author_facet | Dominik Karl Lagler Elisabeth Hannemann Kim Eck Jürgen Klawatsch Doris Seichter Ingolf Russ Christian Mendel Gesine Lühken Stefan Krebs Helmut Blum Maulik Upadhyay Ivica Medugorac |
| author_sort | Dominik Karl Lagler |
| collection | DOAJ |
| description | Using SNP-association analysis and genetic mapping, a SNP and an insertion in and close to HOXB13 associated with short tail length is identified in Merino sheep, which may be a target for safely selecting shorter tails and improving sheep welfare. |
| first_indexed | 2024-04-12T23:03:59Z |
| format | Article |
| id | doaj.art-d985dd7ee91e413aa12184c7cf781f01 |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-12T23:03:59Z |
| publishDate | 2022-09-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-d985dd7ee91e413aa12184c7cf781f012022-12-22T03:12:59ZengNature PortfolioCommunications Biology2399-36422022-09-015111310.1038/s42003-022-03854-3Fine-mapping and identification of candidate causal genes for tail length in the Merinolandschaf breedDominik Karl Lagler0Elisabeth Hannemann1Kim Eck2Jürgen Klawatsch3Doris Seichter4Ingolf Russ5Christian Mendel6Gesine Lühken7Stefan Krebs8Helmut Blum9Maulik Upadhyay10Ivica Medugorac11Population Genomics Group, Department of Veterinary Sciences, LMU MunichPopulation Genomics Group, Department of Veterinary Sciences, LMU MunichPopulation Genomics Group, Department of Veterinary Sciences, LMU MunichPopulation Genomics Group, Department of Veterinary Sciences, LMU MunichTierzuchtforschung e.V. MünchenTierzuchtforschung e.V. MünchenInstitute for Animal Breeding, Bavarian State Research Center for AgricultureInstitute of Animal Breeding and Genetics, JLU GießenLaboratory for Functional Genome Analysis, Gene Center, Ludwig-Maximilians-University MunichLaboratory for Functional Genome Analysis, Gene Center, Ludwig-Maximilians-University MunichPopulation Genomics Group, Department of Veterinary Sciences, LMU MunichPopulation Genomics Group, Department of Veterinary Sciences, LMU MunichUsing SNP-association analysis and genetic mapping, a SNP and an insertion in and close to HOXB13 associated with short tail length is identified in Merino sheep, which may be a target for safely selecting shorter tails and improving sheep welfare.https://doi.org/10.1038/s42003-022-03854-3 |
| spellingShingle | Dominik Karl Lagler Elisabeth Hannemann Kim Eck Jürgen Klawatsch Doris Seichter Ingolf Russ Christian Mendel Gesine Lühken Stefan Krebs Helmut Blum Maulik Upadhyay Ivica Medugorac Fine-mapping and identification of candidate causal genes for tail length in the Merinolandschaf breed Communications Biology |
| title | Fine-mapping and identification of candidate causal genes for tail length in the Merinolandschaf breed |
| title_full | Fine-mapping and identification of candidate causal genes for tail length in the Merinolandschaf breed |
| title_fullStr | Fine-mapping and identification of candidate causal genes for tail length in the Merinolandschaf breed |
| title_full_unstemmed | Fine-mapping and identification of candidate causal genes for tail length in the Merinolandschaf breed |
| title_short | Fine-mapping and identification of candidate causal genes for tail length in the Merinolandschaf breed |
| title_sort | fine mapping and identification of candidate causal genes for tail length in the merinolandschaf breed |
| url | https://doi.org/10.1038/s42003-022-03854-3 |
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