3D convolutional neural networks predict cellular metabolic pathway use from fluorescence lifetime decay data

3D convolutional neural networks predict cellular metabolic pathway use from fluorescence lifetime decay data

Fluorescence lifetime imaging of the co-enzyme reduced nicotinamide adenine dinucleotide (NADH) offers a label-free approach for detecting cellular metabolic perturbations. However, the relationships between variations in NADH lifetime and metabolic pathway changes are complex, preventing robust int...

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Bibliographic Details
Main Authors: Linghao Hu, Daniela De Hoyos, Yuanjiu Lei, A. Phillip West, Alex J. Walsh
Format: Article
Language:English
Published: AIP Publishing LLC 2024-03-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/5.0188476

Internet

http://dx.doi.org/10.1063/5.0188476

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