Discovery of cell apoptosis regulation genes: Sydney Brenner, John E. Sulston and H. Robert Horvitz (The Nobel Prize in Physiology or Medicine 2002)
The Nobel Prize in Physiology or Medicine 2002 was awarded to Sydney Brenner, Howard Robert Horvitz and John Edward Sulston for their discoveries concerning “genetic regulation of organ development and programmed cell death”. The scientists studied cell division and differentiation in the nematode...
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| Format: | Article |
| Language: | English |
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National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry
2021-06-01
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| Series: | The Ukrainian Biochemical Journal |
| Subjects: | |
| Online Access: | http://ukrbiochemjournal.org/wp-content/uploads/2021/07/Grigorieva_3_21.pdf |
| _version_ | 1797427457631977472 |
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| author | M. V. Grigorieva V. M. Danilova S. V. Komisarenko |
| author_facet | M. V. Grigorieva V. M. Danilova S. V. Komisarenko |
| author_sort | M. V. Grigorieva |
| collection | DOAJ |
| description | The Nobel Prize in Physiology or Medicine 2002 was awarded to Sydney Brenner, Howard Robert Horvitz and John Edward Sulston for their discoveries concerning “genetic regulation of organ development and programmed cell death”. The scientists studied cell division and differentiation in the nematode Caenorhabditis elegans from the fertilized egg to the adult organism. As a result of their studies, key genes regulating organ development and programmed cell death (apoptosis) were identified, and corresponding genes were shown to exist in higher species, including humans. These discoveries shed light on the pathogenesis of many diseases and were important for further medical research. |
| first_indexed | 2024-03-09T08:44:19Z |
| format | Article |
| id | doaj.art-d98d1bf39afa426d93f355a9dc6d4563 |
| institution | Directory Open Access Journal |
| issn | 2409-4943 2413-5003 |
| language | English |
| last_indexed | 2024-03-09T08:44:19Z |
| publishDate | 2021-06-01 |
| publisher | National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry |
| record_format | Article |
| series | The Ukrainian Biochemical Journal |
| spelling | doaj.art-d98d1bf39afa426d93f355a9dc6d45632023-12-02T15:44:20ZengNational Academy of Sciences of Ukraine, Palladin Institute of BiochemistryThe Ukrainian Biochemical Journal2409-49432413-50032021-06-0193311112210.15407/ubj93.03.111Discovery of cell apoptosis regulation genes: Sydney Brenner, John E. Sulston and H. Robert Horvitz (The Nobel Prize in Physiology or Medicine 2002)M. V. Grigorieva0https://orcid.org/0000-0002-0397-7154V. M. Danilova1S. V. Komisarenko2https://orcid.org/0000-0002-3244-3194Palladin Biochemistry Institute, National Academy of Sciences of Ukraine, KyivPalladin Biochemistry Institute, National Academy of Sciences of Ukraine, KyivPalladin Biochemistry Institute, National Academy of Sciences of Ukraine, KyivThe Nobel Prize in Physiology or Medicine 2002 was awarded to Sydney Brenner, Howard Robert Horvitz and John Edward Sulston for their discoveries concerning “genetic regulation of organ development and programmed cell death”. The scientists studied cell division and differentiation in the nematode Caenorhabditis elegans from the fertilized egg to the adult organism. As a result of their studies, key genes regulating organ development and programmed cell death (apoptosis) were identified, and corresponding genes were shown to exist in higher species, including humans. These discoveries shed light on the pathogenesis of many diseases and were important for further medical research.http://ukrbiochemjournal.org/wp-content/uploads/2021/07/Grigorieva_3_21.pdfapoptosiscaenorhabditis elegansgenetic regulation of organ developmenth. robert horvitzjohn e. sulstonsydney brenner |
| spellingShingle | M. V. Grigorieva V. M. Danilova S. V. Komisarenko Discovery of cell apoptosis regulation genes: Sydney Brenner, John E. Sulston and H. Robert Horvitz (The Nobel Prize in Physiology or Medicine 2002) The Ukrainian Biochemical Journal apoptosis caenorhabditis elegans genetic regulation of organ development h. robert horvitz john e. sulston sydney brenner |
| title | Discovery of cell apoptosis regulation genes: Sydney Brenner, John E. Sulston and H. Robert Horvitz (The Nobel Prize in Physiology or Medicine 2002) |
| title_full | Discovery of cell apoptosis regulation genes: Sydney Brenner, John E. Sulston and H. Robert Horvitz (The Nobel Prize in Physiology or Medicine 2002) |
| title_fullStr | Discovery of cell apoptosis regulation genes: Sydney Brenner, John E. Sulston and H. Robert Horvitz (The Nobel Prize in Physiology or Medicine 2002) |
| title_full_unstemmed | Discovery of cell apoptosis regulation genes: Sydney Brenner, John E. Sulston and H. Robert Horvitz (The Nobel Prize in Physiology or Medicine 2002) |
| title_short | Discovery of cell apoptosis regulation genes: Sydney Brenner, John E. Sulston and H. Robert Horvitz (The Nobel Prize in Physiology or Medicine 2002) |
| title_sort | discovery of cell apoptosis regulation genes sydney brenner john e sulston and h robert horvitz the nobel prize in physiology or medicine 2002 |
| topic | apoptosis caenorhabditis elegans genetic regulation of organ development h. robert horvitz john e. sulston sydney brenner |
| url | http://ukrbiochemjournal.org/wp-content/uploads/2021/07/Grigorieva_3_21.pdf |
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