Physical activity pattern of patients with interstitial lung disease compared to patients with COPD: A propensity-matched study
<h4>Introduction</h4> Physical activity (PA) is reduced in patients with interstitial lung disease (ILD) and chronic obstructive pulmonary disease (COPD). Evidence about the PA pattern of patients with ILD is scarce. If PA of patients with ILD would be comparable to COPD, it is tempting...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2022-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678311/?tool=EBI |
| _version_ | 1811322132636893184 |
|---|---|
| author | Sofie Breuls Cintia Pereira de Araujo Astrid Blondeel Jonas Yserbyt Wim Janssens Wim Wuyts Thierry Troosters Heleen Demeyer |
| author_facet | Sofie Breuls Cintia Pereira de Araujo Astrid Blondeel Jonas Yserbyt Wim Janssens Wim Wuyts Thierry Troosters Heleen Demeyer |
| author_sort | Sofie Breuls |
| collection | DOAJ |
| description | <h4>Introduction</h4> Physical activity (PA) is reduced in patients with interstitial lung disease (ILD) and chronic obstructive pulmonary disease (COPD). Evidence about the PA pattern of patients with ILD is scarce. If PA of patients with ILD would be comparable to COPD, it is tempting to speculate that existing interventions focusing on enhancing PA could be as effective in ILD as already shown in COPD. Therefore, we aimed to compare PA and the correlates with PA in matched patients with ILD, COPD, and healthy subjects. <h4>Materials and methods</h4> Patients with ILD (n = 45), COPD (n = 45) and healthy subjects (n = 30) were propensity matched. PA level, pattern, and PA correlations with lung function and physical performance (6-minute walking distance and quadriceps force) were compared between groups. <h4>Results</h4> Daily number of steps was similar in both patient groups (mean±SE: 5631±459 for ILD, 5544±547 for COPD, p = 0.900), but significantly lower compared to healthy subjects (10031±536, p<0.001 for both). Mean intensity of PA tended to be lower in the ILD group (mean±SE metabolic equivalents of task per day: 1.41±0.04) compared to COPD (1.52±0.05, p = 0.074) and healthy individuals (1.67±0.04, p<0.001). The pattern of PA over one day was found to be similar between the three groups. Lastly, the correlation between PA and 6-minute walking distance was significantly weaker in patients with ILD compared to patients with COPD (respectively r = 0.348 and r = 0.739; p<0.05 for both). <h4>Conclusions</h4> For a given functional reserve, patients with ILD perform an equal amount of steps but perform PA at lower intensity compared to patients with COPD. Both groups are less active compared to healthy control subjects. Functional exercise capacity was shown to be only moderately related to PA. This can potentially influence the effectiveness of PA interventions that can be expected. |
| first_indexed | 2024-04-13T13:29:50Z |
| format | Article |
| id | doaj.art-d992758333f64b95bf44f49fa4848926 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-13T13:29:50Z |
| publishDate | 2022-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-d992758333f64b95bf44f49fa48489262022-12-22T02:45:01ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-011711Physical activity pattern of patients with interstitial lung disease compared to patients with COPD: A propensity-matched studySofie BreulsCintia Pereira de AraujoAstrid BlondeelJonas YserbytWim JanssensWim WuytsThierry TroostersHeleen Demeyer<h4>Introduction</h4> Physical activity (PA) is reduced in patients with interstitial lung disease (ILD) and chronic obstructive pulmonary disease (COPD). Evidence about the PA pattern of patients with ILD is scarce. If PA of patients with ILD would be comparable to COPD, it is tempting to speculate that existing interventions focusing on enhancing PA could be as effective in ILD as already shown in COPD. Therefore, we aimed to compare PA and the correlates with PA in matched patients with ILD, COPD, and healthy subjects. <h4>Materials and methods</h4> Patients with ILD (n = 45), COPD (n = 45) and healthy subjects (n = 30) were propensity matched. PA level, pattern, and PA correlations with lung function and physical performance (6-minute walking distance and quadriceps force) were compared between groups. <h4>Results</h4> Daily number of steps was similar in both patient groups (mean±SE: 5631±459 for ILD, 5544±547 for COPD, p = 0.900), but significantly lower compared to healthy subjects (10031±536, p<0.001 for both). Mean intensity of PA tended to be lower in the ILD group (mean±SE metabolic equivalents of task per day: 1.41±0.04) compared to COPD (1.52±0.05, p = 0.074) and healthy individuals (1.67±0.04, p<0.001). The pattern of PA over one day was found to be similar between the three groups. Lastly, the correlation between PA and 6-minute walking distance was significantly weaker in patients with ILD compared to patients with COPD (respectively r = 0.348 and r = 0.739; p<0.05 for both). <h4>Conclusions</h4> For a given functional reserve, patients with ILD perform an equal amount of steps but perform PA at lower intensity compared to patients with COPD. Both groups are less active compared to healthy control subjects. Functional exercise capacity was shown to be only moderately related to PA. This can potentially influence the effectiveness of PA interventions that can be expected.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678311/?tool=EBI |
| spellingShingle | Sofie Breuls Cintia Pereira de Araujo Astrid Blondeel Jonas Yserbyt Wim Janssens Wim Wuyts Thierry Troosters Heleen Demeyer Physical activity pattern of patients with interstitial lung disease compared to patients with COPD: A propensity-matched study PLoS ONE |
| title | Physical activity pattern of patients with interstitial lung disease compared to patients with COPD: A propensity-matched study |
| title_full | Physical activity pattern of patients with interstitial lung disease compared to patients with COPD: A propensity-matched study |
| title_fullStr | Physical activity pattern of patients with interstitial lung disease compared to patients with COPD: A propensity-matched study |
| title_full_unstemmed | Physical activity pattern of patients with interstitial lung disease compared to patients with COPD: A propensity-matched study |
| title_short | Physical activity pattern of patients with interstitial lung disease compared to patients with COPD: A propensity-matched study |
| title_sort | physical activity pattern of patients with interstitial lung disease compared to patients with copd a propensity matched study |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678311/?tool=EBI |
| work_keys_str_mv | AT sofiebreuls physicalactivitypatternofpatientswithinterstitiallungdiseasecomparedtopatientswithcopdapropensitymatchedstudy AT cintiapereiradearaujo physicalactivitypatternofpatientswithinterstitiallungdiseasecomparedtopatientswithcopdapropensitymatchedstudy AT astridblondeel physicalactivitypatternofpatientswithinterstitiallungdiseasecomparedtopatientswithcopdapropensitymatchedstudy AT jonasyserbyt physicalactivitypatternofpatientswithinterstitiallungdiseasecomparedtopatientswithcopdapropensitymatchedstudy AT wimjanssens physicalactivitypatternofpatientswithinterstitiallungdiseasecomparedtopatientswithcopdapropensitymatchedstudy AT wimwuyts physicalactivitypatternofpatientswithinterstitiallungdiseasecomparedtopatientswithcopdapropensitymatchedstudy AT thierrytroosters physicalactivitypatternofpatientswithinterstitiallungdiseasecomparedtopatientswithcopdapropensitymatchedstudy AT heleendemeyer physicalactivitypatternofpatientswithinterstitiallungdiseasecomparedtopatientswithcopdapropensitymatchedstudy |