Management of patients at the hepatopancreatobiliary unit of a London teaching hospital during the COVID-19 pandemic
Abstract To mitigate COVID-19-related shortage of treatment capacity, the hepatopancreatobiliary (HPB) unit of the Royal Free Hospital London (RFHL) transferred its practice to independent hospitals in Central London through the North Central London Cancer Alliance. The aim of this study was to crit...
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-08-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-40264-9 |
| _version_ | 1797559573777743872 |
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| author | Sebastian M. Staubli Dimitri A. Raptis Shahi Ghani Brian R. Davidson Giuseppe K. Fusai Charles Imber Sateesh Iype David Nasralla Theodora Pissanou Sakhawat Rahman Dinesh Sharma Pascale Tinguely Fares Haddad Miranda Dodd Chris Dann David Walker Joerg-Matthias Pollok On behalf of the Royal Free Hospital London HPB team |
| author_facet | Sebastian M. Staubli Dimitri A. Raptis Shahi Ghani Brian R. Davidson Giuseppe K. Fusai Charles Imber Sateesh Iype David Nasralla Theodora Pissanou Sakhawat Rahman Dinesh Sharma Pascale Tinguely Fares Haddad Miranda Dodd Chris Dann David Walker Joerg-Matthias Pollok On behalf of the Royal Free Hospital London HPB team |
| author_sort | Sebastian M. Staubli |
| collection | DOAJ |
| description | Abstract To mitigate COVID-19-related shortage of treatment capacity, the hepatopancreatobiliary (HPB) unit of the Royal Free Hospital London (RFHL) transferred its practice to independent hospitals in Central London through the North Central London Cancer Alliance. The aim of this study was to critically assess this strategy and evaluate perioperative outcomes. Prospectively collected data were reviewed on all patients who were treated under the RFHL HPB unit in six hospitals between November 2020 and October 2021. A total of 1541 patients were included, as follows: 1246 (81%) at the RFHL, 41 (3%) at the Chase Farm Hospital, 23 (2%) at the Whittington Hospital, 207 (13%) at the Princess Grace Hospital, 12 (1%) at the Wellington Hospital and 12 (1%) at the Lister Hospital, Chelsea. Across all institutions, overall complication rate were 40%, major complication (Clavien–Dindo grade ≥ 3a) rate were 11% and mortality rates were 1.4%, respectively. In COVID-19-positive patients (n = 28), compared with negative patients, complication rate and mortality rates were increased tenfold. Outsourcing HPB patients, including their specialist care, to surrounding institutions was safe and ensured ongoing treatment with comparable outcomes among the institutions during the COVID-19 pandemic. Due to the lack of direct comparison with a non-pandemic cohort, these results can strictly only be applied within a pandemic setting. |
| first_indexed | 2024-03-10T17:47:16Z |
| format | Article |
| id | doaj.art-d99972a402c94baebd5279506bea2663 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-10T17:47:16Z |
| publishDate | 2023-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-d99972a402c94baebd5279506bea26632023-11-20T09:29:52ZengNature PortfolioScientific Reports2045-23222023-08-011311910.1038/s41598-023-40264-9Management of patients at the hepatopancreatobiliary unit of a London teaching hospital during the COVID-19 pandemicSebastian M. Staubli0Dimitri A. Raptis1Shahi Ghani2Brian R. Davidson3Giuseppe K. Fusai4Charles Imber5Sateesh Iype6David Nasralla7Theodora Pissanou8Sakhawat Rahman9Dinesh Sharma10Pascale Tinguely11Fares Haddad12Miranda Dodd13Chris Dann14David Walker15Joerg-Matthias Pollok16On behalf of the Royal Free Hospital London HPB teamDepartment of HPB Surgery and Liver Transplantation, Clinical Service of HPB Surgery and Liver Transplantation, Royal Free London NHS Foundation Trust, UCL PartnersDepartment of HPB Surgery and Liver Transplantation, Clinical Service of HPB Surgery and Liver Transplantation, Royal Free London NHS Foundation Trust, UCL PartnersDepartment of HPB Surgery and Liver Transplantation, Clinical Service of HPB Surgery and Liver Transplantation, Royal Free London NHS Foundation Trust, UCL PartnersDepartment of HPB Surgery and Liver Transplantation, Clinical Service of HPB Surgery and Liver Transplantation, Royal Free London NHS Foundation Trust, UCL PartnersDepartment of HPB Surgery and Liver Transplantation, Clinical Service of HPB Surgery and Liver Transplantation, Royal Free London NHS Foundation Trust, UCL PartnersDepartment of HPB Surgery and Liver Transplantation, Clinical Service of HPB Surgery and Liver Transplantation, Royal Free London NHS Foundation Trust, UCL PartnersDepartment of HPB Surgery and Liver Transplantation, Clinical Service of HPB Surgery and Liver Transplantation, Royal Free London NHS Foundation Trust, UCL PartnersDepartment of HPB Surgery and Liver Transplantation, Clinical Service of HPB Surgery and Liver Transplantation, Royal Free London NHS Foundation Trust, UCL PartnersDepartment of HPB Surgery and Liver Transplantation, Clinical Service of HPB Surgery and Liver Transplantation, Royal Free London NHS Foundation Trust, UCL PartnersDepartment of HPB Surgery and Liver Transplantation, Clinical Service of HPB Surgery and Liver Transplantation, Royal Free London NHS Foundation Trust, UCL PartnersDepartment of HPB Surgery and Liver Transplantation, Clinical Service of HPB Surgery and Liver Transplantation, Royal Free London NHS Foundation Trust, UCL PartnersDepartment of HPB Surgery and Liver Transplantation, Clinical Service of HPB Surgery and Liver Transplantation, Royal Free London NHS Foundation Trust, UCL PartnersDivision of Surgery and Interventional Science, University College LondonThe Princess Grace Hospital (HCA Healthcare UK)Department of Trauma and Orthopaedics, University College London Hospitals NHS Foundation Trust, LondonDivision of Surgery and Interventional Science, University College LondonDepartment of HPB Surgery and Liver Transplantation, Clinical Service of HPB Surgery and Liver Transplantation, Royal Free London NHS Foundation Trust, UCL PartnersAbstract To mitigate COVID-19-related shortage of treatment capacity, the hepatopancreatobiliary (HPB) unit of the Royal Free Hospital London (RFHL) transferred its practice to independent hospitals in Central London through the North Central London Cancer Alliance. The aim of this study was to critically assess this strategy and evaluate perioperative outcomes. Prospectively collected data were reviewed on all patients who were treated under the RFHL HPB unit in six hospitals between November 2020 and October 2021. A total of 1541 patients were included, as follows: 1246 (81%) at the RFHL, 41 (3%) at the Chase Farm Hospital, 23 (2%) at the Whittington Hospital, 207 (13%) at the Princess Grace Hospital, 12 (1%) at the Wellington Hospital and 12 (1%) at the Lister Hospital, Chelsea. Across all institutions, overall complication rate were 40%, major complication (Clavien–Dindo grade ≥ 3a) rate were 11% and mortality rates were 1.4%, respectively. In COVID-19-positive patients (n = 28), compared with negative patients, complication rate and mortality rates were increased tenfold. Outsourcing HPB patients, including their specialist care, to surrounding institutions was safe and ensured ongoing treatment with comparable outcomes among the institutions during the COVID-19 pandemic. Due to the lack of direct comparison with a non-pandemic cohort, these results can strictly only be applied within a pandemic setting.https://doi.org/10.1038/s41598-023-40264-9 |
| spellingShingle | Sebastian M. Staubli Dimitri A. Raptis Shahi Ghani Brian R. Davidson Giuseppe K. Fusai Charles Imber Sateesh Iype David Nasralla Theodora Pissanou Sakhawat Rahman Dinesh Sharma Pascale Tinguely Fares Haddad Miranda Dodd Chris Dann David Walker Joerg-Matthias Pollok On behalf of the Royal Free Hospital London HPB team Management of patients at the hepatopancreatobiliary unit of a London teaching hospital during the COVID-19 pandemic Scientific Reports |
| title | Management of patients at the hepatopancreatobiliary unit of a London teaching hospital during the COVID-19 pandemic |
| title_full | Management of patients at the hepatopancreatobiliary unit of a London teaching hospital during the COVID-19 pandemic |
| title_fullStr | Management of patients at the hepatopancreatobiliary unit of a London teaching hospital during the COVID-19 pandemic |
| title_full_unstemmed | Management of patients at the hepatopancreatobiliary unit of a London teaching hospital during the COVID-19 pandemic |
| title_short | Management of patients at the hepatopancreatobiliary unit of a London teaching hospital during the COVID-19 pandemic |
| title_sort | management of patients at the hepatopancreatobiliary unit of a london teaching hospital during the covid 19 pandemic |
| url | https://doi.org/10.1038/s41598-023-40264-9 |
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