Graves' disease: pathophysiological aspects and considerations about using the chemometric analysis in the study of the disease
Graves’ disease is an immune system disorder that results in the overproduction of thyroid hormones (hyperthyroidism). Thyroid disorders are a societal problem of great public concern because of their high prevalence. This problem can affect the well-being and quality of life of patien...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Pensoft Publishers
2021-08-01
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| Series: | Folia Medica |
| Subjects: | |
| Online Access: | https://foliamedica.bg/article/57193/download/pdf/ |
| _version_ | 1818977290410786816 |
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| author | Pavlina M. Koseva Zdravko A. Kamenov Mariana M. Nikolova Pavlina A. Andreeva-Gateva |
| author_facet | Pavlina M. Koseva Zdravko A. Kamenov Mariana M. Nikolova Pavlina A. Andreeva-Gateva |
| author_sort | Pavlina M. Koseva |
| collection | DOAJ |
| description | Graves’ disease is an immune system disorder that results in the overproduction of thyroid hormones (hyperthyroidism). Thyroid disorders are a societal problem of great public concern because of their high prevalence. This problem can affect the well-being and quality of life of patients. The predisposing factors leading to this disease are not yet fully established and are likely to be interconnected in a complex way. Chemometric analysis allows for the detection of specific relationships between the medical parameter measurements obtained from the patients in an observation group, and the identification of patterns of similarity between these patients. It is not commonly used in clinical trials; however, it can provide reliable information which may help in creating more successful, individualised treatment strategies for established groups (patterns) of patients.The aim of this review is to summarize the latest knowledge about the risk factors for Graves’ disease and considerations about using the chemometric analysis in the study of the disease. |
| first_indexed | 2024-12-20T16:25:23Z |
| format | Article |
| id | doaj.art-d99e9490735b48d9b2a62909418cdb11 |
| institution | Directory Open Access Journal |
| issn | 1314-2143 |
| language | English |
| last_indexed | 2024-12-20T16:25:23Z |
| publishDate | 2021-08-01 |
| publisher | Pensoft Publishers |
| record_format | Article |
| series | Folia Medica |
| spelling | doaj.art-d99e9490735b48d9b2a62909418cdb112022-12-21T19:33:28ZengPensoft PublishersFolia Medica1314-21432021-08-0163446747410.3897/folmed.63.e5719357193Graves' disease: pathophysiological aspects and considerations about using the chemometric analysis in the study of the diseasePavlina M. Koseva0Zdravko A. Kamenov1Mariana M. Nikolova2Pavlina A. Andreeva-Gateva3Medical University of VarnaMedical University of SofiaMiddlesex UniversityMedical University of SofiaGraves’ disease is an immune system disorder that results in the overproduction of thyroid hormones (hyperthyroidism). Thyroid disorders are a societal problem of great public concern because of their high prevalence. This problem can affect the well-being and quality of life of patients. The predisposing factors leading to this disease are not yet fully established and are likely to be interconnected in a complex way. Chemometric analysis allows for the detection of specific relationships between the medical parameter measurements obtained from the patients in an observation group, and the identification of patterns of similarity between these patients. It is not commonly used in clinical trials; however, it can provide reliable information which may help in creating more successful, individualised treatment strategies for established groups (patterns) of patients.The aim of this review is to summarize the latest knowledge about the risk factors for Graves’ disease and considerations about using the chemometric analysis in the study of the disease.https://foliamedica.bg/article/57193/download/pdf/autoimmunitygoiterreviewrisk factors |
| spellingShingle | Pavlina M. Koseva Zdravko A. Kamenov Mariana M. Nikolova Pavlina A. Andreeva-Gateva Graves' disease: pathophysiological aspects and considerations about using the chemometric analysis in the study of the disease Folia Medica autoimmunity goiter review risk factors |
| title | Graves' disease: pathophysiological aspects and considerations about using the chemometric analysis in the study of the disease |
| title_full | Graves' disease: pathophysiological aspects and considerations about using the chemometric analysis in the study of the disease |
| title_fullStr | Graves' disease: pathophysiological aspects and considerations about using the chemometric analysis in the study of the disease |
| title_full_unstemmed | Graves' disease: pathophysiological aspects and considerations about using the chemometric analysis in the study of the disease |
| title_short | Graves' disease: pathophysiological aspects and considerations about using the chemometric analysis in the study of the disease |
| title_sort | graves amp 39 disease pathophysiological aspects and considerations about using the chemometric analysis in the study of the disease |
| topic | autoimmunity goiter review risk factors |
| url | https://foliamedica.bg/article/57193/download/pdf/ |
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