Efficacy and Safety of Second and Third-Generation Laser Balloon for Paroxysmal Atrial Fibrillation Ablation Compared to Radiofrequency Ablation: A Matched-Cohort
Laser balloon (LB) has emerged as an interesting strategy for pulmonary vein isolation in paroxysmal atrial fibrillation (AF). A third-generation LB has recently been developed, allowing a continuous ablation set. We aimed to compare the results from our center’s experience with second and third-gen...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-12-01
|
| Series: | Journal of Cardiovascular Development and Disease |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2308-3425/8/12/183 |
| _version_ | 1797503539678806016 |
|---|---|
| author | Charles Guenancia Nefissa Hammache Clémence Docq Karim Benali Darren Hooks Mathieu Echivard Nathalie Pace Isabelle Magnin-Poull Christian de Chillou Jean-Marc Sellal |
| author_facet | Charles Guenancia Nefissa Hammache Clémence Docq Karim Benali Darren Hooks Mathieu Echivard Nathalie Pace Isabelle Magnin-Poull Christian de Chillou Jean-Marc Sellal |
| author_sort | Charles Guenancia |
| collection | DOAJ |
| description | Laser balloon (LB) has emerged as an interesting strategy for pulmonary vein isolation in paroxysmal atrial fibrillation (AF). A third-generation LB has recently been developed, allowing a continuous ablation set. We aimed to compare the results from our center’s experience with second and third-generation LBs to a cohort of matched patients who had undergone radiofrequency ablation (RFA) with contact-force catheters. This retrospective monocenter case-control study included our first 50 LB paroxysmal AF ablations (26 second and 24 third-generation LB) and 50 RFA controls, matched on age, sex and left atrial dilation. The two groups had similar baseline parameters. LB procedures were significantly shorter than RFA (129 (110–160) vs. 160 (119–198) min, <i>p</i> = 0.007). During AF ablation, two major complications occurred in each group. At the one-year follow-up, AF recurrence was diagnosed in 7 (14%) of the LB group vs. 14 (28%) of the RFA group (<i>p</i> = 0.14). Moreover, we observed that third-generation LB procedures were associated with shorter laser applications (22 (19–29) vs. 69 (55–76) min, <i>p</i> < 0.001) and procedural durations (111 (100–128) vs. 151.5 (128.5–167) min, <i>p</i> < 0.001) compared to second-generation LB procedures. In the context of the major increase in the number of AF ablations, LB demonstrated consistent results in terms of clinical success, complications and also reduced procedure durations compared to RFA. |
| first_indexed | 2024-03-10T03:52:07Z |
| format | Article |
| id | doaj.art-d99f972a6cb34389951f0faa441a5935 |
| institution | Directory Open Access Journal |
| issn | 2308-3425 |
| language | English |
| last_indexed | 2024-03-10T03:52:07Z |
| publishDate | 2021-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Cardiovascular Development and Disease |
| spelling | doaj.art-d99f972a6cb34389951f0faa441a59352023-11-23T08:55:04ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252021-12-0181218310.3390/jcdd8120183Efficacy and Safety of Second and Third-Generation Laser Balloon for Paroxysmal Atrial Fibrillation Ablation Compared to Radiofrequency Ablation: A Matched-CohortCharles Guenancia0Nefissa Hammache1Clémence Docq2Karim Benali3Darren Hooks4Mathieu Echivard5Nathalie Pace6Isabelle Magnin-Poull7Christian de Chillou8Jean-Marc Sellal9Département de Cardiologie, CHRU de Nancy, 54500 Vandœuvre-lès-Nancy, FranceDépartement de Cardiologie, CHRU de Nancy, 54500 Vandœuvre-lès-Nancy, FranceDépartement de Cardiologie, CHRU de Nancy, 54500 Vandœuvre-lès-Nancy, FranceDépartement de Cardiologie, CHRU de Nancy, 54500 Vandœuvre-lès-Nancy, FranceCardiology Department, Wellington Hospital, Wellington 6021, New ZealandDépartement de Cardiologie, CHRU de Nancy, 54500 Vandœuvre-lès-Nancy, FranceDépartement de Cardiologie, CHRU de Nancy, 54500 Vandœuvre-lès-Nancy, FranceDépartement de Cardiologie, CHRU de Nancy, 54500 Vandœuvre-lès-Nancy, FranceDépartement de Cardiologie, CHRU de Nancy, 54500 Vandœuvre-lès-Nancy, FranceDépartement de Cardiologie, CHRU de Nancy, 54500 Vandœuvre-lès-Nancy, FranceLaser balloon (LB) has emerged as an interesting strategy for pulmonary vein isolation in paroxysmal atrial fibrillation (AF). A third-generation LB has recently been developed, allowing a continuous ablation set. We aimed to compare the results from our center’s experience with second and third-generation LBs to a cohort of matched patients who had undergone radiofrequency ablation (RFA) with contact-force catheters. This retrospective monocenter case-control study included our first 50 LB paroxysmal AF ablations (26 second and 24 third-generation LB) and 50 RFA controls, matched on age, sex and left atrial dilation. The two groups had similar baseline parameters. LB procedures were significantly shorter than RFA (129 (110–160) vs. 160 (119–198) min, <i>p</i> = 0.007). During AF ablation, two major complications occurred in each group. At the one-year follow-up, AF recurrence was diagnosed in 7 (14%) of the LB group vs. 14 (28%) of the RFA group (<i>p</i> = 0.14). Moreover, we observed that third-generation LB procedures were associated with shorter laser applications (22 (19–29) vs. 69 (55–76) min, <i>p</i> < 0.001) and procedural durations (111 (100–128) vs. 151.5 (128.5–167) min, <i>p</i> < 0.001) compared to second-generation LB procedures. In the context of the major increase in the number of AF ablations, LB demonstrated consistent results in terms of clinical success, complications and also reduced procedure durations compared to RFA.https://www.mdpi.com/2308-3425/8/12/183atrial fibrillationablationlaserradiofrequencyparoxysmal |
| spellingShingle | Charles Guenancia Nefissa Hammache Clémence Docq Karim Benali Darren Hooks Mathieu Echivard Nathalie Pace Isabelle Magnin-Poull Christian de Chillou Jean-Marc Sellal Efficacy and Safety of Second and Third-Generation Laser Balloon for Paroxysmal Atrial Fibrillation Ablation Compared to Radiofrequency Ablation: A Matched-Cohort Journal of Cardiovascular Development and Disease atrial fibrillation ablation laser radiofrequency paroxysmal |
| title | Efficacy and Safety of Second and Third-Generation Laser Balloon for Paroxysmal Atrial Fibrillation Ablation Compared to Radiofrequency Ablation: A Matched-Cohort |
| title_full | Efficacy and Safety of Second and Third-Generation Laser Balloon for Paroxysmal Atrial Fibrillation Ablation Compared to Radiofrequency Ablation: A Matched-Cohort |
| title_fullStr | Efficacy and Safety of Second and Third-Generation Laser Balloon for Paroxysmal Atrial Fibrillation Ablation Compared to Radiofrequency Ablation: A Matched-Cohort |
| title_full_unstemmed | Efficacy and Safety of Second and Third-Generation Laser Balloon for Paroxysmal Atrial Fibrillation Ablation Compared to Radiofrequency Ablation: A Matched-Cohort |
| title_short | Efficacy and Safety of Second and Third-Generation Laser Balloon for Paroxysmal Atrial Fibrillation Ablation Compared to Radiofrequency Ablation: A Matched-Cohort |
| title_sort | efficacy and safety of second and third generation laser balloon for paroxysmal atrial fibrillation ablation compared to radiofrequency ablation a matched cohort |
| topic | atrial fibrillation ablation laser radiofrequency paroxysmal |
| url | https://www.mdpi.com/2308-3425/8/12/183 |
| work_keys_str_mv | AT charlesguenancia efficacyandsafetyofsecondandthirdgenerationlaserballoonforparoxysmalatrialfibrillationablationcomparedtoradiofrequencyablationamatchedcohort AT nefissahammache efficacyandsafetyofsecondandthirdgenerationlaserballoonforparoxysmalatrialfibrillationablationcomparedtoradiofrequencyablationamatchedcohort AT clemencedocq efficacyandsafetyofsecondandthirdgenerationlaserballoonforparoxysmalatrialfibrillationablationcomparedtoradiofrequencyablationamatchedcohort AT karimbenali efficacyandsafetyofsecondandthirdgenerationlaserballoonforparoxysmalatrialfibrillationablationcomparedtoradiofrequencyablationamatchedcohort AT darrenhooks efficacyandsafetyofsecondandthirdgenerationlaserballoonforparoxysmalatrialfibrillationablationcomparedtoradiofrequencyablationamatchedcohort AT mathieuechivard efficacyandsafetyofsecondandthirdgenerationlaserballoonforparoxysmalatrialfibrillationablationcomparedtoradiofrequencyablationamatchedcohort AT nathaliepace efficacyandsafetyofsecondandthirdgenerationlaserballoonforparoxysmalatrialfibrillationablationcomparedtoradiofrequencyablationamatchedcohort AT isabellemagninpoull efficacyandsafetyofsecondandthirdgenerationlaserballoonforparoxysmalatrialfibrillationablationcomparedtoradiofrequencyablationamatchedcohort AT christiandechillou efficacyandsafetyofsecondandthirdgenerationlaserballoonforparoxysmalatrialfibrillationablationcomparedtoradiofrequencyablationamatchedcohort AT jeanmarcsellal efficacyandsafetyofsecondandthirdgenerationlaserballoonforparoxysmalatrialfibrillationablationcomparedtoradiofrequencyablationamatchedcohort |