Long term health-related quality of life in survivors of sepsis in South West Wales: an epidemiological study.
INTRODUCTION: Survivors of sepsis report persistent problems that can last years after hospital discharge. The main aim of this study was to investigate long-term health-related quality of life in survivors of SIRS and sepsis compared with Welsh normative data, controlling for age, length of stay an...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4280200?pdf=render |
| _version_ | 1811338108372779008 |
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| author | Ceri E Battle Gareth Davies Phillip A Evans |
| author_facet | Ceri E Battle Gareth Davies Phillip A Evans |
| author_sort | Ceri E Battle |
| collection | DOAJ |
| description | INTRODUCTION: Survivors of sepsis report persistent problems that can last years after hospital discharge. The main aim of this study was to investigate long-term health-related quality of life in survivors of SIRS and sepsis compared with Welsh normative data, controlling for age, length of stay and pre-existing conditions. The second aim was to investigate any differences in long-term health-related quality of life specifically with the patients categorised into three groups; SIRS, uncomplicated sepsis and severe sepsis/septic shock. METHODS: A prospective study design was used in order to investigate all sepsis patients either presenting to the Emergency Department or admitted to the Intensive Care Unit of a regional trauma centre. Baseline demographics, clinical characteristics and outcomes were collected and surviving patients were sent a SF-12v2 survey at between six months to two years post-hospital discharge. RESULTS: Quality of life was significantly reduced in all patients when compared to local normative data (all p<0.0001). Reductions in the physical components of health-related quality of life were more pronounced in severe sepsis/septic shock patients when compared to uncomplicated sepsis and SIRS patients, when controlling for age, pre-existing conditions, hospital and ICU length of stay. CONCLUSIONS: This is the first observational study to specifically focus on the different groups of SIRS and sepsis patients to assess long-term quality of life. Local population norms were used for comparison, rather than UK-wide norms that fail to reflect the intricacies of a country's population. |
| first_indexed | 2024-04-13T18:05:52Z |
| format | Article |
| id | doaj.art-d9a27d06c51d46328424035f68618ea6 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-13T18:05:52Z |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-d9a27d06c51d46328424035f68618ea62022-12-22T02:36:05ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-01912e11630410.1371/journal.pone.0116304Long term health-related quality of life in survivors of sepsis in South West Wales: an epidemiological study.Ceri E BattleGareth DaviesPhillip A EvansINTRODUCTION: Survivors of sepsis report persistent problems that can last years after hospital discharge. The main aim of this study was to investigate long-term health-related quality of life in survivors of SIRS and sepsis compared with Welsh normative data, controlling for age, length of stay and pre-existing conditions. The second aim was to investigate any differences in long-term health-related quality of life specifically with the patients categorised into three groups; SIRS, uncomplicated sepsis and severe sepsis/septic shock. METHODS: A prospective study design was used in order to investigate all sepsis patients either presenting to the Emergency Department or admitted to the Intensive Care Unit of a regional trauma centre. Baseline demographics, clinical characteristics and outcomes were collected and surviving patients were sent a SF-12v2 survey at between six months to two years post-hospital discharge. RESULTS: Quality of life was significantly reduced in all patients when compared to local normative data (all p<0.0001). Reductions in the physical components of health-related quality of life were more pronounced in severe sepsis/septic shock patients when compared to uncomplicated sepsis and SIRS patients, when controlling for age, pre-existing conditions, hospital and ICU length of stay. CONCLUSIONS: This is the first observational study to specifically focus on the different groups of SIRS and sepsis patients to assess long-term quality of life. Local population norms were used for comparison, rather than UK-wide norms that fail to reflect the intricacies of a country's population.http://europepmc.org/articles/PMC4280200?pdf=render |
| spellingShingle | Ceri E Battle Gareth Davies Phillip A Evans Long term health-related quality of life in survivors of sepsis in South West Wales: an epidemiological study. PLoS ONE |
| title | Long term health-related quality of life in survivors of sepsis in South West Wales: an epidemiological study. |
| title_full | Long term health-related quality of life in survivors of sepsis in South West Wales: an epidemiological study. |
| title_fullStr | Long term health-related quality of life in survivors of sepsis in South West Wales: an epidemiological study. |
| title_full_unstemmed | Long term health-related quality of life in survivors of sepsis in South West Wales: an epidemiological study. |
| title_short | Long term health-related quality of life in survivors of sepsis in South West Wales: an epidemiological study. |
| title_sort | long term health related quality of life in survivors of sepsis in south west wales an epidemiological study |
| url | http://europepmc.org/articles/PMC4280200?pdf=render |
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