Bloom Helicase Along with Recombinase Rad51 Repairs the Mitochondrial Genome of the Malaria Parasite

Bloom Helicase Along with Recombinase Rad51 Repairs the Mitochondrial Genome of the Malaria Parasite

ABSTRACT The homologous recombination (HR) pathway has been implicated as the predominant mechanism for the repair of chromosomal DNA double-strand breaks (DSBs) of the malarial parasite. Although the extrachromosomal mitochondrial genome of this parasite experiences a greater number of DSBs due to...

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Bibliographic Details
Main Authors: Payal Jha, Abhilasha Gahlawat, Sunanda Bhattacharyya, Sandeep Dey, Kota Arun Kumar, Mrinal Kanti Bhattacharyya
Format: Article
Language:English
Published: American Society for Microbiology 2021-12-01
Series:mSphere
Subjects:
PfBlm
PfRad51
mitochondria
DNA repair
homologous recombination
Plasmodium falciparum
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00718-21

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