sCD28, sCD80, sCTLA-4, and sBTLA Are Promising Markers in Diagnostic and Therapeutic Approaches for Aseptic Loosening and Periprosthetic Joint Infection

sCD28, sCD80, sCTLA-4, and sBTLA Are Promising Markers in Diagnostic and Therapeutic Approaches for Aseptic Loosening and Periprosthetic Joint Infection

Aseptic prosthetic loosening and periprosthetic joint infections (PJI) are among the most frequent complications after total knee/hip joint arthroplasty (TJA). Current research efforts focus on understanding the involvement of the immune system in these frequent complications. Different immune cell...

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Bibliographic Details
Main Authors: Jil M. Jubel, Thomas M. Randau, Janine Becker-Gotot, Sebastian Scheidt, Matthias D. Wimmer, Hendrik Kohlhof, Christof Burger, Dieter C. Wirtz, Frank A. Schildberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
aseptic loosening
periprosthetic joint infection
immunoregulatory markers
sCD28
sCD80
sCTLA-4
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.687065/full

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