Hyperbaric Oxygen in Otorhinolaryngology: Current Concepts in Management and Therapy

Background: In otorhinolaryngology and head and neck surgery, oxygen is a therapeutic tool used for various pathologies. Oxidative stress is the imbalance between the production of free radicals (ROS) and the antioxidant capacity of the body, which can represent the pathogenesis of several pathologi...

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Autores principales: Andrea Collettini, Federica Zoccali, Christian Barbato, Antonio Minni
Formato: Artículo
Lenguaje:English
Publicado: MDPI AG 2024-04-01
Colección:Oxygen
Materias:
Acceso en línea:https://www.mdpi.com/2673-9801/4/2/10
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author Andrea Collettini
Federica Zoccali
Christian Barbato
Antonio Minni
author_facet Andrea Collettini
Federica Zoccali
Christian Barbato
Antonio Minni
author_sort Andrea Collettini
collection DOAJ
description Background: In otorhinolaryngology and head and neck surgery, oxygen is a therapeutic tool used for various pathologies. Oxidative stress is the imbalance between the production of free radicals (ROS) and the antioxidant capacity of the body, which can represent the pathogenesis of several pathologies or contribute to their worsening. This narrative review aims to analyze the benefits, indications, and side effects of hyperbaric oxygen therapy (HBOT) in different head and neck disorders. Methods: The search was carried out on multiple electronic databases such as PubMed and Google Scholar, and prospective, randomized, and reviewed studies were analyzed from January 1982 to February 2024. Results and Conclusions: The most common tools used to manage oxidative stress in the ear, nose, and throat (ENT) field are continuous positive airway pressure (CPAP) and HBOT. A common ENT pathology, while the latter can be used for osteoradionecrosis treatment in head and neck cancer patients, infections, malignant external otitis, head and neck reconstruction, facial cosmetic surgery, and among patients with sudden sensorineural hearing loss. From our analysis, it emerged that HBOT is a currently used effective therapy in various ENT pathologies’ treatment, alone or in association with other treatments; it can guarantee functional recovery and healing depending on the type of pathology for which it is used and on its severity.
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spelling doaj.art-d9a78924a1b04466b10f2395c59b967a2024-06-26T15:02:05ZengMDPI AGOxygen2673-98012024-04-014215016210.3390/oxygen4020010Hyperbaric Oxygen in Otorhinolaryngology: Current Concepts in Management and TherapyAndrea Collettini0Federica Zoccali1Christian Barbato2Antonio Minni3Department of Sense Organs, Sapienza University of Rome, 00161 Roma, ItalyDepartment of Sense Organs, Sapienza University of Rome, 00161 Roma, ItalyInstitute of Biochemistry and Cell Biology (IBBC-CNR), Sapienza University Rome, Policlinico Umberto I, 00161 Roma, ItalyDepartment of Sense Organs, Sapienza University of Rome, 00161 Roma, ItalyBackground: In otorhinolaryngology and head and neck surgery, oxygen is a therapeutic tool used for various pathologies. Oxidative stress is the imbalance between the production of free radicals (ROS) and the antioxidant capacity of the body, which can represent the pathogenesis of several pathologies or contribute to their worsening. This narrative review aims to analyze the benefits, indications, and side effects of hyperbaric oxygen therapy (HBOT) in different head and neck disorders. Methods: The search was carried out on multiple electronic databases such as PubMed and Google Scholar, and prospective, randomized, and reviewed studies were analyzed from January 1982 to February 2024. Results and Conclusions: The most common tools used to manage oxidative stress in the ear, nose, and throat (ENT) field are continuous positive airway pressure (CPAP) and HBOT. A common ENT pathology, while the latter can be used for osteoradionecrosis treatment in head and neck cancer patients, infections, malignant external otitis, head and neck reconstruction, facial cosmetic surgery, and among patients with sudden sensorineural hearing loss. From our analysis, it emerged that HBOT is a currently used effective therapy in various ENT pathologies’ treatment, alone or in association with other treatments; it can guarantee functional recovery and healing depending on the type of pathology for which it is used and on its severity.https://www.mdpi.com/2673-9801/4/2/10hyperbaric oxygen therapyENToxidative stress
spellingShingle Andrea Collettini
Federica Zoccali
Christian Barbato
Antonio Minni
Hyperbaric Oxygen in Otorhinolaryngology: Current Concepts in Management and Therapy
Oxygen
hyperbaric oxygen therapy
ENT
oxidative stress
title Hyperbaric Oxygen in Otorhinolaryngology: Current Concepts in Management and Therapy
title_full Hyperbaric Oxygen in Otorhinolaryngology: Current Concepts in Management and Therapy
title_fullStr Hyperbaric Oxygen in Otorhinolaryngology: Current Concepts in Management and Therapy
title_full_unstemmed Hyperbaric Oxygen in Otorhinolaryngology: Current Concepts in Management and Therapy
title_short Hyperbaric Oxygen in Otorhinolaryngology: Current Concepts in Management and Therapy
title_sort hyperbaric oxygen in otorhinolaryngology current concepts in management and therapy
topic hyperbaric oxygen therapy
ENT
oxidative stress
url https://www.mdpi.com/2673-9801/4/2/10
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