Orolingual Angioedema After Intravenous Tissue Plasminogen Activator in a Patient with Insular Cortex Ischemia: A Case Report
Intravenous tissue plasminogen activator (tPA) increases survival rates without sequelae in acute ischemic stroke. Complications and management of this treatment have become more important with the increasing use of tPA. An 80-year-old male patient was admitted with a sudden-onset speech disorder an...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2020-12-01
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| Series: | Türk Nöroloji Dergisi |
| Subjects: | |
| Online Access: | https://tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-04864&look4= |
| _version_ | 1797919471706308608 |
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| author | Aydın Talip Yıldoğan Fettah Eren Şerefnur Öztürk |
| author_facet | Aydın Talip Yıldoğan Fettah Eren Şerefnur Öztürk |
| author_sort | Aydın Talip Yıldoğan |
| collection | DOAJ |
| description | Intravenous tissue plasminogen activator (tPA) increases survival rates without sequelae in acute ischemic stroke. Complications and management of this treatment have become more important with the increasing use of tPA. An 80-year-old male patient was admitted with a sudden-onset speech disorder and loss of strength in his right arm, which started 3 hours ago. Magnetic resonance imaging revealed acute ischemia localized in the left insular cortex. Lip and tongue swelling, difficulty in speaking, and deepening in voice were observed in the 30th minute of infusion. There was mild respiratory distress. Orolingual angioedema was diagnosed. He completely recovered after treatment. Angioedema is a rare but potentially life-threatening complication of tPA. When this clinical symptom occurs, it should be recognized and treated quickly. This report aims to reveal the relationship of this rare complication with the localization of the ischemia. |
| first_indexed | 2024-04-10T13:46:04Z |
| format | Article |
| id | doaj.art-d9a79d5284c044b2a9bebc117ed403ca |
| institution | Directory Open Access Journal |
| issn | 1309-2545 |
| language | English |
| last_indexed | 2024-04-10T13:46:04Z |
| publishDate | 2020-12-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Nöroloji Dergisi |
| spelling | doaj.art-d9a79d5284c044b2a9bebc117ed403ca2023-02-15T16:10:59ZengGalenos YayineviTürk Nöroloji Dergisi1309-25452020-12-0126434634810.4274/tnd.2020.04864Orolingual Angioedema After Intravenous Tissue Plasminogen Activator in a Patient with Insular Cortex Ischemia: A Case ReportAydın Talip Yıldoğan0https://orcid.org/0000-0002-9482-6203Fettah Eren1https://orcid.org/0000-0001-6834-0827Şerefnur Öztürk2https://orcid.org/0000-0001-8986-155XSelcuk University Faculty of Medicine, Department of Neurology, Konya, TurkeyKonya Training and Research Hospital, Clinic of Neurology, Konya, TurkeySelcuk University Faculty of Medicine, Department of Neurology, Konya, TurkeyIntravenous tissue plasminogen activator (tPA) increases survival rates without sequelae in acute ischemic stroke. Complications and management of this treatment have become more important with the increasing use of tPA. An 80-year-old male patient was admitted with a sudden-onset speech disorder and loss of strength in his right arm, which started 3 hours ago. Magnetic resonance imaging revealed acute ischemia localized in the left insular cortex. Lip and tongue swelling, difficulty in speaking, and deepening in voice were observed in the 30th minute of infusion. There was mild respiratory distress. Orolingual angioedema was diagnosed. He completely recovered after treatment. Angioedema is a rare but potentially life-threatening complication of tPA. When this clinical symptom occurs, it should be recognized and treated quickly. This report aims to reveal the relationship of this rare complication with the localization of the ischemia.https://tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-04864&look4=intravenous thrombolysisstrokeinsulaangioedema |
| spellingShingle | Aydın Talip Yıldoğan Fettah Eren Şerefnur Öztürk Orolingual Angioedema After Intravenous Tissue Plasminogen Activator in a Patient with Insular Cortex Ischemia: A Case Report Türk Nöroloji Dergisi intravenous thrombolysis stroke insula angioedema |
| title | Orolingual Angioedema After Intravenous Tissue Plasminogen Activator in a Patient with Insular Cortex Ischemia: A Case Report |
| title_full | Orolingual Angioedema After Intravenous Tissue Plasminogen Activator in a Patient with Insular Cortex Ischemia: A Case Report |
| title_fullStr | Orolingual Angioedema After Intravenous Tissue Plasminogen Activator in a Patient with Insular Cortex Ischemia: A Case Report |
| title_full_unstemmed | Orolingual Angioedema After Intravenous Tissue Plasminogen Activator in a Patient with Insular Cortex Ischemia: A Case Report |
| title_short | Orolingual Angioedema After Intravenous Tissue Plasminogen Activator in a Patient with Insular Cortex Ischemia: A Case Report |
| title_sort | orolingual angioedema after intravenous tissue plasminogen activator in a patient with insular cortex ischemia a case report |
| topic | intravenous thrombolysis stroke insula angioedema |
| url | https://tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-04864&look4= |
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