Diagnosis of patients with Lynch syndrome lacking the Amsterdam II or Bethesda criteria
Abstract Background Lynch Syndrome (LS) is an autosomal dominant inheritance disorder characterized by genetic predisposition to develop cancer, caused by pathogenic variants in the genes of the mismatch repair system. Cases are detected by implementing the Amsterdam II and the revised Bethesda crit...
Main Authors: | Miguel Angel Trujillo-Rojas, María de la Luz Ayala-Madrigal, Melva Gutiérrez-Angulo, Anahí González-Mercado, José Miguel Moreno-Ortiz |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-10-01
|
Series: | Hereditary Cancer in Clinical Practice |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13053-023-00266-0 |
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