A novel epitope-blocking ELISA for specific and sensitive detection of antibodies against H5-subtype influenza virus hemagglutinin

A novel epitope-blocking ELISA for specific and sensitive detection of antibodies against H5-subtype influenza virus hemagglutinin

Abstract Background H5-subtype highly pathogenic (HP) avian influenza viruses (AIVs) cause high mortality in domestic birds and sporadic infections in humans with a frequently fatal outcome, while H5N1 viruses have pandemic potential. Due to veterinary and public health significance, these HPAIVs, a...

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Bibliographic Details
Main Authors: Violetta Sączyńska, Katarzyna Florys-Jankowska, Anna Porębska, Violetta Cecuda-Adamczewska
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Virology Journal
Subjects:
Avian influenza viruses
Hemagglutinin
Monoclonal antibodies
Antibody detection
Blocking ELISA
H5
Online Access:https://doi.org/10.1186/s12985-021-01564-6

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