Ultraviolet-Visible-Near Infrared Spectroscopy May Aid in the Qualitative Assessment of Early-Stage Cartilage Degradation
Purpose: To assess the potential of ultraviolet-visible near-infrared spectroscopy to provide quantitative information on the cartilage surface at early osteoarthritis. Methods: We used a similar source and optical path to a standard arthroscope and constraining input to the range available to a sta...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-02-01
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| Series: | Arthroscopy, Sports Medicine, and Rehabilitation |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666061X23001931 |
| _version_ | 1797302502103711744 |
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| author | Ying-chun Chen, D.Phil. Hsing-Po Huang, Ph.D. |
| author_facet | Ying-chun Chen, D.Phil. Hsing-Po Huang, Ph.D. |
| author_sort | Ying-chun Chen, D.Phil. |
| collection | DOAJ |
| description | Purpose: To assess the potential of ultraviolet-visible near-infrared spectroscopy to provide quantitative information on the cartilage surface at early osteoarthritis. Methods: We used a similar source and optical path to a standard arthroscope and constraining input to the range available to a standard detector/camera, further capturing and analyzing spectral information quantitatively in terms of specific electronic absorbance bands and scattering from the cartilage surface, with a focus on the early stages of degradation. Results: The ratio of the 320-nm and longer than 500-nm absorbances produced a distinct change from the normal to diseased states. The slopes between the wavelengths of 600 and 980 nm may show the transition of the single fibril to fibril bundles that occurs during early stages disease. Conclusions: Ultraviolet-visible near-infrared spectroscopy has good potential for use in integrated arthroscopic assessment. Clinical Relevance: This raises the possibility of advancing arthroscopy from a qualitative to a quantitative tool, without requiring modification of either the radiation (the light source and path) or instrumentation (the arthroscope itself) delivered to the patient, thus allowing a low-cost yet potentially high-value technology. |
| first_indexed | 2024-03-07T23:38:45Z |
| format | Article |
| id | doaj.art-d9b3f15cf80d44a5b1029356040e721c |
| institution | Directory Open Access Journal |
| issn | 2666-061X |
| language | English |
| last_indexed | 2024-03-07T23:38:45Z |
| publishDate | 2024-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Arthroscopy, Sports Medicine, and Rehabilitation |
| spelling | doaj.art-d9b3f15cf80d44a5b1029356040e721c2024-02-20T04:19:47ZengElsevierArthroscopy, Sports Medicine, and Rehabilitation2666-061X2024-02-0161100842Ultraviolet-Visible-Near Infrared Spectroscopy May Aid in the Qualitative Assessment of Early-Stage Cartilage DegradationYing-chun Chen, D.Phil.0Hsing-Po Huang, Ph.D.1Botnar Research Centre, NDORMS, University of Oxford, Oxford, United Kingdom; Department of Mechanical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan; Address correspondence to Dr. Ying-chun Chen, D.Phil., Department of Mechanical Engineering, National Taiwan University of Science and Technology.Department of Mechanical Engineering, National Taipei University of Technology. Taipei, TaiwanPurpose: To assess the potential of ultraviolet-visible near-infrared spectroscopy to provide quantitative information on the cartilage surface at early osteoarthritis. Methods: We used a similar source and optical path to a standard arthroscope and constraining input to the range available to a standard detector/camera, further capturing and analyzing spectral information quantitatively in terms of specific electronic absorbance bands and scattering from the cartilage surface, with a focus on the early stages of degradation. Results: The ratio of the 320-nm and longer than 500-nm absorbances produced a distinct change from the normal to diseased states. The slopes between the wavelengths of 600 and 980 nm may show the transition of the single fibril to fibril bundles that occurs during early stages disease. Conclusions: Ultraviolet-visible near-infrared spectroscopy has good potential for use in integrated arthroscopic assessment. Clinical Relevance: This raises the possibility of advancing arthroscopy from a qualitative to a quantitative tool, without requiring modification of either the radiation (the light source and path) or instrumentation (the arthroscope itself) delivered to the patient, thus allowing a low-cost yet potentially high-value technology.http://www.sciencedirect.com/science/article/pii/S2666061X23001931 |
| spellingShingle | Ying-chun Chen, D.Phil. Hsing-Po Huang, Ph.D. Ultraviolet-Visible-Near Infrared Spectroscopy May Aid in the Qualitative Assessment of Early-Stage Cartilage Degradation Arthroscopy, Sports Medicine, and Rehabilitation |
| title | Ultraviolet-Visible-Near Infrared Spectroscopy May Aid in the Qualitative Assessment of Early-Stage Cartilage Degradation |
| title_full | Ultraviolet-Visible-Near Infrared Spectroscopy May Aid in the Qualitative Assessment of Early-Stage Cartilage Degradation |
| title_fullStr | Ultraviolet-Visible-Near Infrared Spectroscopy May Aid in the Qualitative Assessment of Early-Stage Cartilage Degradation |
| title_full_unstemmed | Ultraviolet-Visible-Near Infrared Spectroscopy May Aid in the Qualitative Assessment of Early-Stage Cartilage Degradation |
| title_short | Ultraviolet-Visible-Near Infrared Spectroscopy May Aid in the Qualitative Assessment of Early-Stage Cartilage Degradation |
| title_sort | ultraviolet visible near infrared spectroscopy may aid in the qualitative assessment of early stage cartilage degradation |
| url | http://www.sciencedirect.com/science/article/pii/S2666061X23001931 |
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