BIVALIRUDIN AND PERCUTANEOUS CORONARY INTERVENTIONS IN PATIENTS WITH ACUTE CORONARY SYNDROME: THEORY AND PRACTICE
This analytical paper presents the key information on the mechanism of action of a direct thrombin inhibitor – bivalirudin. The difference between bivalirudin and unfractionated or low molecular weight heparins, as well as fondaparinux, in terms of the mechanism of action, pharmacokinetics, and phar...
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2012-06-01
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| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/1236 |
| _version_ | 1797857117293510656 |
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| author | O. V. Averkov |
| author_facet | O. V. Averkov |
| author_sort | O. V. Averkov |
| collection | DOAJ |
| description | This analytical paper presents the key information on the mechanism of action of a direct thrombin inhibitor – bivalirudin. The difference between bivalirudin and unfractionated or low molecular weight heparins, as well as fondaparinux, in terms of the mechanism of action, pharmacokinetics, and pharmacodynamics, is discussed. The results of clinical trials of bivalirudin and the position of this medication in the current clinical guidelines on acute coronary syndrome treatment are summarized. A detailed description of bivalirudin dosage is presented, together with the recommendations on its effective and safe use in clinical practice. |
| first_indexed | 2024-04-09T20:51:27Z |
| format | Article |
| id | doaj.art-d9b5e7772de8442b8116be8e22b9e5a4 |
| institution | Directory Open Access Journal |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| last_indexed | 2024-04-09T20:51:27Z |
| publishDate | 2012-06-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj.art-d9b5e7772de8442b8116be8e22b9e5a42023-03-29T21:23:19Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202012-06-01031021121038BIVALIRUDIN AND PERCUTANEOUS CORONARY INTERVENTIONS IN PATIENTS WITH ACUTE CORONARY SYNDROME: THEORY AND PRACTICEO. V. Averkov0City Clinical Hospital № 15, named after O. M. Filatov, Russian University of People’s Friendship, MoscowThis analytical paper presents the key information on the mechanism of action of a direct thrombin inhibitor – bivalirudin. The difference between bivalirudin and unfractionated or low molecular weight heparins, as well as fondaparinux, in terms of the mechanism of action, pharmacokinetics, and pharmacodynamics, is discussed. The results of clinical trials of bivalirudin and the position of this medication in the current clinical guidelines on acute coronary syndrome treatment are summarized. A detailed description of bivalirudin dosage is presented, together with the recommendations on its effective and safe use in clinical practice.https://russjcardiol.elpub.ru/jour/article/view/1236acute coronary syndromeanticoagulantsbivalirudinpercutaneous coronary interventions |
| spellingShingle | O. V. Averkov BIVALIRUDIN AND PERCUTANEOUS CORONARY INTERVENTIONS IN PATIENTS WITH ACUTE CORONARY SYNDROME: THEORY AND PRACTICE Российский кардиологический журнал acute coronary syndrome anticoagulants bivalirudin percutaneous coronary interventions |
| title | BIVALIRUDIN AND PERCUTANEOUS CORONARY INTERVENTIONS IN PATIENTS WITH ACUTE CORONARY SYNDROME: THEORY AND PRACTICE |
| title_full | BIVALIRUDIN AND PERCUTANEOUS CORONARY INTERVENTIONS IN PATIENTS WITH ACUTE CORONARY SYNDROME: THEORY AND PRACTICE |
| title_fullStr | BIVALIRUDIN AND PERCUTANEOUS CORONARY INTERVENTIONS IN PATIENTS WITH ACUTE CORONARY SYNDROME: THEORY AND PRACTICE |
| title_full_unstemmed | BIVALIRUDIN AND PERCUTANEOUS CORONARY INTERVENTIONS IN PATIENTS WITH ACUTE CORONARY SYNDROME: THEORY AND PRACTICE |
| title_short | BIVALIRUDIN AND PERCUTANEOUS CORONARY INTERVENTIONS IN PATIENTS WITH ACUTE CORONARY SYNDROME: THEORY AND PRACTICE |
| title_sort | bivalirudin and percutaneous coronary interventions in patients with acute coronary syndrome theory and practice |
| topic | acute coronary syndrome anticoagulants bivalirudin percutaneous coronary interventions |
| url | https://russjcardiol.elpub.ru/jour/article/view/1236 |
| work_keys_str_mv | AT ovaverkov bivalirudinandpercutaneouscoronaryinterventionsinpatientswithacutecoronarysyndrometheoryandpractice |