TT‐seq captures enhancer landscapes immediately after T‐cell stimulation

TT‐seq captures enhancer landscapes immediately after T‐cell stimulation

Abstract To monitor transcriptional regulation in human cells, rapid changes in enhancer and promoter activity must be captured with high sensitivity and temporal resolution. Here, we show that the recently established protocol TT‐seq (“transient transcriptome sequencing”) can monitor rapid changes...

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Bibliographic Details
Main Authors: Margaux Michel, Carina Demel, Benedikt Zacher, Björn Schwalb, Stefan Krebs, Helmut Blum, Julien Gagneur, Patrick Cramer
Format: Article
Language:English
Published: Springer Nature 2017-03-01
Series:Molecular Systems Biology
Subjects:
enhancers
functional genomics
promoters
T‐cell response
transcriptome analysis
Online Access:https://doi.org/10.15252/msb.20167507

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