Dipeptidyl Peptidase IV Inhibitory Peptides from Chickpea Proteins (<i>Cicer arietinum</i> L.): Pharmacokinetics, Molecular Interactions, and Multi-Bioactivities

Dipeptidyl Peptidase IV Inhibitory Peptides from Chickpea Proteins (<i>Cicer arietinum</i> L.): Pharmacokinetics, Molecular Interactions, and Multi-Bioactivities

Chickpea (<i>Cicer arietinum</i> L.) peptides can inhibit dipeptidyl peptidase IV (DPP-IV), an important type 2 diabetes mellitus therapeutic target. The molecular interactions between the inhibitory peptides and the active site of DPP-IV have not been thoroughly examined, nor have their...

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Bibliographic Details
Main Authors: José Antonio Mora-Melgem, Jesús Gilberto Arámburo-Gálvez, Feliznando Isidro Cárdenas-Torres, Jhonatan Gonzalez-Santamaria, Giovanni Isaí Ramírez-Torres, Aldo Alejandro Arvizu-Flores, Oscar Gerardo Figueroa-Salcido, Noé Ontiveros
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Pharmaceuticals
Subjects:
chickpea
bioactive peptides
DPP-IV inhibitors
in silico
molecular docking
ADMET
Online Access:https://www.mdpi.com/1424-8247/16/8/1109

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