Intranasal vaccination with murabutide enhances humoral and mucosal immune responses to a virus-like particle vaccine.
Murabutide (MB) is a synthetic immunomodulator recognized by the nucleotide-binding oligomerization domain-containing protein 2 (NOD2) receptor on mammalian cells. MB has previously been approved for testing in multiple human clinical trials to determine its value as an antiviral therapeutic, and as...
Những tác giả chính: | , |
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Định dạng: | Bài viết |
Ngôn ngữ: | English |
Được phát hành: |
Public Library of Science (PLoS)
2012-01-01
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Loạt: | PLoS ONE |
Truy cập trực tuyến: | http://europepmc.org/articles/PMC3405106?pdf=render |