Ellagic Acid and Schisandrins: Natural Biaryl Polyphenols with Therapeutic Potential to Overcome Multidrug Resistance in Cancer

Multidrug resistance (MDR) is one of the major clinical challenges in cancer treatment and compromises the effectiveness of conventional anticancer chemotherapeutics. Among known mechanisms of drug resistance, drug efflux via ATP binding cassette (ABC) transporters, namely P-glycoprotein (P-gp) has...

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Bibliographic Details
Main Authors: Sabesan Yoganathan, Anushan Alagaratnam, Nikita Acharekar, Jing Kong
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/2/458

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