Meningitis due to a Combination of Streptococcus mitis and Neisseria subflava: A Case Report

We report a rare case of meningitis due to a combination of Streptococcus mitis and Neisseria subflava. An 80-year-old female had a 4-year history of type II diabetes mellitus (DM) and an 11-year history of rheumatoid arthritis, which was treated with prednisolone, tacrolimus, and methotrexate. One...

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Main Authors: Kana Fukumoto, Yasuhiro Manabe, Shunya Fujiwara, Yoshio Omote, Hisashi Narai, Haruto Yamada, Takashi Saito, Koji Abe
Format: Article
Language:English
Published: Karger Publishers 2018-07-01
Series:Case Reports in Neurology
Subjects:
Online Access:https://www.karger.com/Article/FullText/490695
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author Kana Fukumoto
Yasuhiro Manabe
Shunya Fujiwara
Yoshio Omote
Hisashi Narai
Haruto Yamada
Takashi Saito
Koji Abe
author_facet Kana Fukumoto
Yasuhiro Manabe
Shunya Fujiwara
Yoshio Omote
Hisashi Narai
Haruto Yamada
Takashi Saito
Koji Abe
author_sort Kana Fukumoto
collection DOAJ
description We report a rare case of meningitis due to a combination of Streptococcus mitis and Neisseria subflava. An 80-year-old female had a 4-year history of type II diabetes mellitus (DM) and an 11-year history of rheumatoid arthritis, which was treated with prednisolone, tacrolimus, and methotrexate. One month after the removal of a dental implant, she complained of a disturbance of consciousness and suffered a convulsion. A cerebrospinal fluid culture was found to be positive for both S. mitis and N. subflava. After 14 days of antibiotic treatment with 4 g/day ceftriaxone, her stiff neck, somnolence, and laboratory data greatly improved, and she was successfully discharged at 27 days after admission. Although both S. mitis and N. subflava are generally considered to be benign bacteria, they can cause meningitis in patients with the following risk factors: older age, on immunosuppressive treatment, DM, or dental treatment.
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spelling doaj.art-d9cce0ce3dc24519ab2c80972fcdffd02022-12-22T01:48:29ZengKarger PublishersCase Reports in Neurology1662-680X2018-07-0110217718010.1159/000490695490695Meningitis due to a Combination of Streptococcus mitis and Neisseria subflava: A Case ReportKana FukumotoYasuhiro ManabeShunya FujiwaraYoshio OmoteHisashi NaraiHaruto YamadaTakashi SaitoKoji AbeWe report a rare case of meningitis due to a combination of Streptococcus mitis and Neisseria subflava. An 80-year-old female had a 4-year history of type II diabetes mellitus (DM) and an 11-year history of rheumatoid arthritis, which was treated with prednisolone, tacrolimus, and methotrexate. One month after the removal of a dental implant, she complained of a disturbance of consciousness and suffered a convulsion. A cerebrospinal fluid culture was found to be positive for both S. mitis and N. subflava. After 14 days of antibiotic treatment with 4 g/day ceftriaxone, her stiff neck, somnolence, and laboratory data greatly improved, and she was successfully discharged at 27 days after admission. Although both S. mitis and N. subflava are generally considered to be benign bacteria, they can cause meningitis in patients with the following risk factors: older age, on immunosuppressive treatment, DM, or dental treatment.https://www.karger.com/Article/FullText/490695Streptococcus mitisNeisseria subflavaBacterial meningitisCompromised host
spellingShingle Kana Fukumoto
Yasuhiro Manabe
Shunya Fujiwara
Yoshio Omote
Hisashi Narai
Haruto Yamada
Takashi Saito
Koji Abe
Meningitis due to a Combination of Streptococcus mitis and Neisseria subflava: A Case Report
Case Reports in Neurology
Streptococcus mitis
Neisseria subflava
Bacterial meningitis
Compromised host
title Meningitis due to a Combination of Streptococcus mitis and Neisseria subflava: A Case Report
title_full Meningitis due to a Combination of Streptococcus mitis and Neisseria subflava: A Case Report
title_fullStr Meningitis due to a Combination of Streptococcus mitis and Neisseria subflava: A Case Report
title_full_unstemmed Meningitis due to a Combination of Streptococcus mitis and Neisseria subflava: A Case Report
title_short Meningitis due to a Combination of Streptococcus mitis and Neisseria subflava: A Case Report
title_sort meningitis due to a combination of streptococcus mitis and neisseria subflava a case report
topic Streptococcus mitis
Neisseria subflava
Bacterial meningitis
Compromised host
url https://www.karger.com/Article/FullText/490695
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