Host Cell S Phase Restricts <italic toggle="yes">Legionella pneumophila</italic> Intracellular Replication by Destabilizing the Membrane-Bound Replication Compartment

Host Cell S Phase Restricts <italic toggle="yes">Legionella pneumophila</italic> Intracellular Replication by Destabilizing the Membrane-Bound Replication Compartment

ABSTRACT Legionella pneumophila grows within cells ranging from environmental amoebae to human macrophages. In spite of this conserved strategy of pathogenesis, identification of host factors that restrict L. pneumophila intracellular replication has not been extended outside components of the mamma...

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Bibliographic Details
Main Authors: Dennise A. de Jesús-Díaz, Connor Murphy, Asaf Sol, Marion Dorer, Ralph R. Isberg
Format: Article
Language:English
Published: American Society for Microbiology 2017-09-01
Series:mBio
Subjects:
Drosophila
Legionella pneumophila
RNA interference
cell cycle
intracellular bacteria
secretion systems
Online Access:https://journals.asm.org/doi/10.1128/mBio.02345-16

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