Inflammatory impact on tissues surrounding the dental implant of singular abutments bonded onto titanium base – A randomized controlled trial

Introduction: In dental implants, the biochemical connection between titanium (ti) and bony tissue has been well established. The properties of dental implants such as osseointegration and stability depend upon composition, design of the implant, connection, and design of the abutment, and additiona...

Full description

Bibliographic Details
Main Authors: Chetan Chandra, Rapolu Sisir, Ajith A Chandy, Sharwan K Singh, Jagveer S Saluja, Jeevanandam Loganathan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2023;volume=15;issue=5;spage=477;epage=480;aulast=Chandra
_version_ 1827779370680320000
author Chetan Chandra
Rapolu Sisir
Ajith A Chandy
Sharwan K Singh
Jagveer S Saluja
Jeevanandam Loganathan
author_facet Chetan Chandra
Rapolu Sisir
Ajith A Chandy
Sharwan K Singh
Jagveer S Saluja
Jeevanandam Loganathan
author_sort Chetan Chandra
collection DOAJ
description Introduction: In dental implants, the biochemical connection between titanium (ti) and bony tissue has been well established. The properties of dental implants such as osseointegration and stability depend upon composition, design of the implant, connection, and design of the abutment, and additional removal of abutments. Recently, laser-generated micro-grooved surface (LSS) and TI abutments are the main focus of preventing peri-implant inflammation. Objectives: To assess the inflammatory impact of singular abutments bonded onto titanium bases on tissues surrounding the dental implant. Methods: Twenty subjects were enrolled. Only those subjects were enrolled who were scheduled to undergo prosthetic rehabilitation of missing teeth. Random division of subjects was done. Group A: Test abutment group and Group B: Control abutment group. The test abutments comprised Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM) titanium abutments bonded onto titanium abutments. However, control abutments were customized and only one-piece CAD/CAM titanium abutments were enrolled.On 6 months and 12 months of follow-up, the clinical and radiographic examination was done. Assessment of the bone level changes, clinical variables, and IL-1b levels was assessed. Results: Mean IL-1b levels in Group A subjects at baseline, 6 months, and 12 months were 1.52 pg/mL, 1.69 pg/mL, and 1.55 pg/mL, respectively. Mean IL-1b levels among the patients of group B at baseline, 6 months, and 12 months were 1.56 pg/mL, 1.71 pg/mL, and 1.54 pg/mL, respectively. Conclusion: Within the limitation of the study, it can be concluded that the impact on the inflammatory condition of surrounding tissues of dental implant does not vary significantly between single abutments bonded onto Titanium bases and singular abutments.
first_indexed 2024-03-11T14:48:12Z
format Article
id doaj.art-d9da5a3dd6f14ff080e64dfe4f9ae157
institution Directory Open Access Journal
issn 0975-7406
language English
last_indexed 2024-03-11T14:48:12Z
publishDate 2023-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Pharmacy and Bioallied Sciences
spelling doaj.art-d9da5a3dd6f14ff080e64dfe4f9ae1572023-10-30T10:31:54ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0975-74062023-01-0115547748010.4103/jpbs.jpbs_557_22Inflammatory impact on tissues surrounding the dental implant of singular abutments bonded onto titanium base – A randomized controlled trialChetan ChandraRapolu SisirAjith A ChandySharwan K SinghJagveer S SalujaJeevanandam LoganathanIntroduction: In dental implants, the biochemical connection between titanium (ti) and bony tissue has been well established. The properties of dental implants such as osseointegration and stability depend upon composition, design of the implant, connection, and design of the abutment, and additional removal of abutments. Recently, laser-generated micro-grooved surface (LSS) and TI abutments are the main focus of preventing peri-implant inflammation. Objectives: To assess the inflammatory impact of singular abutments bonded onto titanium bases on tissues surrounding the dental implant. Methods: Twenty subjects were enrolled. Only those subjects were enrolled who were scheduled to undergo prosthetic rehabilitation of missing teeth. Random division of subjects was done. Group A: Test abutment group and Group B: Control abutment group. The test abutments comprised Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM) titanium abutments bonded onto titanium abutments. However, control abutments were customized and only one-piece CAD/CAM titanium abutments were enrolled.On 6 months and 12 months of follow-up, the clinical and radiographic examination was done. Assessment of the bone level changes, clinical variables, and IL-1b levels was assessed. Results: Mean IL-1b levels in Group A subjects at baseline, 6 months, and 12 months were 1.52 pg/mL, 1.69 pg/mL, and 1.55 pg/mL, respectively. Mean IL-1b levels among the patients of group B at baseline, 6 months, and 12 months were 1.56 pg/mL, 1.71 pg/mL, and 1.54 pg/mL, respectively. Conclusion: Within the limitation of the study, it can be concluded that the impact on the inflammatory condition of surrounding tissues of dental implant does not vary significantly between single abutments bonded onto Titanium bases and singular abutments.http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2023;volume=15;issue=5;spage=477;epage=480;aulast=Chandradental implantinflammationtitanium-based abutment
spellingShingle Chetan Chandra
Rapolu Sisir
Ajith A Chandy
Sharwan K Singh
Jagveer S Saluja
Jeevanandam Loganathan
Inflammatory impact on tissues surrounding the dental implant of singular abutments bonded onto titanium base – A randomized controlled trial
Journal of Pharmacy and Bioallied Sciences
dental implant
inflammation
titanium-based abutment
title Inflammatory impact on tissues surrounding the dental implant of singular abutments bonded onto titanium base – A randomized controlled trial
title_full Inflammatory impact on tissues surrounding the dental implant of singular abutments bonded onto titanium base – A randomized controlled trial
title_fullStr Inflammatory impact on tissues surrounding the dental implant of singular abutments bonded onto titanium base – A randomized controlled trial
title_full_unstemmed Inflammatory impact on tissues surrounding the dental implant of singular abutments bonded onto titanium base – A randomized controlled trial
title_short Inflammatory impact on tissues surrounding the dental implant of singular abutments bonded onto titanium base – A randomized controlled trial
title_sort inflammatory impact on tissues surrounding the dental implant of singular abutments bonded onto titanium base a randomized controlled trial
topic dental implant
inflammation
titanium-based abutment
url http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2023;volume=15;issue=5;spage=477;epage=480;aulast=Chandra
work_keys_str_mv AT chetanchandra inflammatoryimpactontissuessurroundingthedentalimplantofsingularabutmentsbondedontotitaniumbasearandomizedcontrolledtrial
AT rapolusisir inflammatoryimpactontissuessurroundingthedentalimplantofsingularabutmentsbondedontotitaniumbasearandomizedcontrolledtrial
AT ajithachandy inflammatoryimpactontissuessurroundingthedentalimplantofsingularabutmentsbondedontotitaniumbasearandomizedcontrolledtrial
AT sharwanksingh inflammatoryimpactontissuessurroundingthedentalimplantofsingularabutmentsbondedontotitaniumbasearandomizedcontrolledtrial
AT jagveerssaluja inflammatoryimpactontissuessurroundingthedentalimplantofsingularabutmentsbondedontotitaniumbasearandomizedcontrolledtrial
AT jeevanandamloganathan inflammatoryimpactontissuessurroundingthedentalimplantofsingularabutmentsbondedontotitaniumbasearandomizedcontrolledtrial