Long-Term Outcome of Non-Sustained Ventricular Tachycardia in Structurally Normal Hearts.
The impact of non-sustained ventricular tachycardia (NSVT) on the risk of thromboembolic event and clinical outcomes in patients without structural heart disease remains undetermined. This study aimed to evaluate the association between NSVT and clinical outcomes.The study population of 5903 patient...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2016-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4993359?pdf=render |
| _version_ | 1819174348492111872 |
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| author | Chin-Yu Lin Shih-Lin Chang Fa-Po Chung Yun-Yu Chen Yenn-Jiang Lin Li-Wei Lo Yu-Feng Hu Ta-Chuan Tuan Tze-Fan Chao Jo-Nan Liao Yao-Ting Chang Chung-Hsing Lin Suresh Allamsetty Rohit Walia Abigail Louise D Te Shinya Yamada Shuo-Ju Chiang Hsuan-Ming Tsao Shih-Ann Chen |
| author_facet | Chin-Yu Lin Shih-Lin Chang Fa-Po Chung Yun-Yu Chen Yenn-Jiang Lin Li-Wei Lo Yu-Feng Hu Ta-Chuan Tuan Tze-Fan Chao Jo-Nan Liao Yao-Ting Chang Chung-Hsing Lin Suresh Allamsetty Rohit Walia Abigail Louise D Te Shinya Yamada Shuo-Ju Chiang Hsuan-Ming Tsao Shih-Ann Chen |
| author_sort | Chin-Yu Lin |
| collection | DOAJ |
| description | The impact of non-sustained ventricular tachycardia (NSVT) on the risk of thromboembolic event and clinical outcomes in patients without structural heart disease remains undetermined. This study aimed to evaluate the association between NSVT and clinical outcomes.The study population of 5903 patients was culled from the "Registry of 24-hour ECG monitoring at Taipei Veterans General Hospital" (REMOTE database) between January 1, 2002 and December 31, 2004. Of that total, we enrolled 3767 patients without sustained ventricular tachycardia, structural heart disease, and permanent pacemaker. For purposes of this study, NSVT was defined as 3 or more consecutive beats arising below the atrioventricular node with an RR interval of <600 ms (>100 beats/min) and lasting < 30 seconds.There were 776 deaths, 2042 hospitalizations for any reason, 638 cardiovascular (CV)-related hospitalizations, 350 ischemic strokes, 409 transient ischemic accident (TIA), 368 new-onset heart failure (HF), and 260 new-onset atrial fibrillation (AF) with a mean follow-up duration of 10 ± 1 years. In multivariate analysis, the presence of NSVT was independently associated with death (hazard ratio [HR]: 1.362, 95% confidence interval [CI]: 1.071-1.731), CV hospitalization (HR: 1.527, 95% CI: 1.171-1.992), ischemic stroke (HR: 1.436, 95% CI: 1.014-2.032), TIA (HR 1.483, 95% CI: 1.069-2.057), and new-onset HF (HR: 1.716, 95% CI: 1.243-2.368). There was no significant association between the presence of NSVT and all-cause hospitalization or new-onset AF.In patients without structural heart disease, presence of NSVT on 24-hour monitoring was independently associated with death, CV hospitalization, ischemic stroke, TIA, and new onset heart failure. |
| first_indexed | 2024-12-22T20:37:33Z |
| format | Article |
| id | doaj.art-d9dc103eb4f24730b3abd636064475fc |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-22T20:37:33Z |
| publishDate | 2016-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-d9dc103eb4f24730b3abd636064475fc2022-12-21T18:13:25ZengPublic Library of Science (PLoS)PLoS ONE1932-62032016-01-01118e016018110.1371/journal.pone.0160181Long-Term Outcome of Non-Sustained Ventricular Tachycardia in Structurally Normal Hearts.Chin-Yu LinShih-Lin ChangFa-Po ChungYun-Yu ChenYenn-Jiang LinLi-Wei LoYu-Feng HuTa-Chuan TuanTze-Fan ChaoJo-Nan LiaoYao-Ting ChangChung-Hsing LinSuresh AllamsettyRohit WaliaAbigail Louise D TeShinya YamadaShuo-Ju ChiangHsuan-Ming TsaoShih-Ann ChenThe impact of non-sustained ventricular tachycardia (NSVT) on the risk of thromboembolic event and clinical outcomes in patients without structural heart disease remains undetermined. This study aimed to evaluate the association between NSVT and clinical outcomes.The study population of 5903 patients was culled from the "Registry of 24-hour ECG monitoring at Taipei Veterans General Hospital" (REMOTE database) between January 1, 2002 and December 31, 2004. Of that total, we enrolled 3767 patients without sustained ventricular tachycardia, structural heart disease, and permanent pacemaker. For purposes of this study, NSVT was defined as 3 or more consecutive beats arising below the atrioventricular node with an RR interval of <600 ms (>100 beats/min) and lasting < 30 seconds.There were 776 deaths, 2042 hospitalizations for any reason, 638 cardiovascular (CV)-related hospitalizations, 350 ischemic strokes, 409 transient ischemic accident (TIA), 368 new-onset heart failure (HF), and 260 new-onset atrial fibrillation (AF) with a mean follow-up duration of 10 ± 1 years. In multivariate analysis, the presence of NSVT was independently associated with death (hazard ratio [HR]: 1.362, 95% confidence interval [CI]: 1.071-1.731), CV hospitalization (HR: 1.527, 95% CI: 1.171-1.992), ischemic stroke (HR: 1.436, 95% CI: 1.014-2.032), TIA (HR 1.483, 95% CI: 1.069-2.057), and new-onset HF (HR: 1.716, 95% CI: 1.243-2.368). There was no significant association between the presence of NSVT and all-cause hospitalization or new-onset AF.In patients without structural heart disease, presence of NSVT on 24-hour monitoring was independently associated with death, CV hospitalization, ischemic stroke, TIA, and new onset heart failure.http://europepmc.org/articles/PMC4993359?pdf=render |
| spellingShingle | Chin-Yu Lin Shih-Lin Chang Fa-Po Chung Yun-Yu Chen Yenn-Jiang Lin Li-Wei Lo Yu-Feng Hu Ta-Chuan Tuan Tze-Fan Chao Jo-Nan Liao Yao-Ting Chang Chung-Hsing Lin Suresh Allamsetty Rohit Walia Abigail Louise D Te Shinya Yamada Shuo-Ju Chiang Hsuan-Ming Tsao Shih-Ann Chen Long-Term Outcome of Non-Sustained Ventricular Tachycardia in Structurally Normal Hearts. PLoS ONE |
| title | Long-Term Outcome of Non-Sustained Ventricular Tachycardia in Structurally Normal Hearts. |
| title_full | Long-Term Outcome of Non-Sustained Ventricular Tachycardia in Structurally Normal Hearts. |
| title_fullStr | Long-Term Outcome of Non-Sustained Ventricular Tachycardia in Structurally Normal Hearts. |
| title_full_unstemmed | Long-Term Outcome of Non-Sustained Ventricular Tachycardia in Structurally Normal Hearts. |
| title_short | Long-Term Outcome of Non-Sustained Ventricular Tachycardia in Structurally Normal Hearts. |
| title_sort | long term outcome of non sustained ventricular tachycardia in structurally normal hearts |
| url | http://europepmc.org/articles/PMC4993359?pdf=render |
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