Endovascular Embolization by Transcatheter Delivery of Particles: Past, Present, and Future

Minimally invasive techniques to occlude flow within blood vessels, initially pioneered in the 1970s with autologous materials and subsequently advanced with increasingly sophisticated engineered biomaterials, are routinely performed for a variety of medical conditions. Contemporary interventional r...

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Main Authors: Rahul A. Sheth, Sharjeel Sabir, Savitri Krishnamurthy, Reginald K. Avery, Yu Shrike Zhang, Ali Khademhosseini, Rahmi Oklu
Format: Article
Language:English
Published: MDPI AG 2017-04-01
Series:Journal of Functional Biomaterials
Subjects:
Online Access:http://www.mdpi.com/2079-4983/8/2/12
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author Rahul A. Sheth
Sharjeel Sabir
Savitri Krishnamurthy
Reginald K. Avery
Yu Shrike Zhang
Ali Khademhosseini
Rahmi Oklu
author_facet Rahul A. Sheth
Sharjeel Sabir
Savitri Krishnamurthy
Reginald K. Avery
Yu Shrike Zhang
Ali Khademhosseini
Rahmi Oklu
author_sort Rahul A. Sheth
collection DOAJ
description Minimally invasive techniques to occlude flow within blood vessels, initially pioneered in the 1970s with autologous materials and subsequently advanced with increasingly sophisticated engineered biomaterials, are routinely performed for a variety of medical conditions. Contemporary interventional radiologists have at their disposal a wide armamentarium of occlusive agents to treat a range of disease processes through a small incision in the skin. In this review, we provide a historical perspective on endovascular embolization tools, summarize the current state-of-the-art, and highlight burgeoning technologies that promise to advance the field in the near future.
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spelling doaj.art-d9dcef0ca698411cb5c6d333ebc153122022-12-22T03:59:56ZengMDPI AGJournal of Functional Biomaterials2079-49832017-04-01821210.3390/jfb8020012jfb8020012Endovascular Embolization by Transcatheter Delivery of Particles: Past, Present, and FutureRahul A. Sheth0Sharjeel Sabir1Savitri Krishnamurthy2Reginald K. Avery3Yu Shrike Zhang4Ali Khademhosseini5Rahmi Oklu6Department of Interventional Radiology, Division of Diagnostic Imaging, MD Anderson Cancer Center, Houston, TX 77030, USADepartment of Interventional Radiology, Division of Diagnostic Imaging, MD Anderson Cancer Center, Houston, TX 77030, USADepartment of Pathology, MD Anderson Cancer Center, Houston, TX 77030, USAWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USAWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USAWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USABiomaterials Innovation Research Center, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02139, USAMinimally invasive techniques to occlude flow within blood vessels, initially pioneered in the 1970s with autologous materials and subsequently advanced with increasingly sophisticated engineered biomaterials, are routinely performed for a variety of medical conditions. Contemporary interventional radiologists have at their disposal a wide armamentarium of occlusive agents to treat a range of disease processes through a small incision in the skin. In this review, we provide a historical perspective on endovascular embolization tools, summarize the current state-of-the-art, and highlight burgeoning technologies that promise to advance the field in the near future.http://www.mdpi.com/2079-4983/8/2/12biomaterialsbiomedical devicescardiovascular devicesdrug delivery systemsmicrospheresmicrofluidics
spellingShingle Rahul A. Sheth
Sharjeel Sabir
Savitri Krishnamurthy
Reginald K. Avery
Yu Shrike Zhang
Ali Khademhosseini
Rahmi Oklu
Endovascular Embolization by Transcatheter Delivery of Particles: Past, Present, and Future
Journal of Functional Biomaterials
biomaterials
biomedical devices
cardiovascular devices
drug delivery systems
microspheres
microfluidics
title Endovascular Embolization by Transcatheter Delivery of Particles: Past, Present, and Future
title_full Endovascular Embolization by Transcatheter Delivery of Particles: Past, Present, and Future
title_fullStr Endovascular Embolization by Transcatheter Delivery of Particles: Past, Present, and Future
title_full_unstemmed Endovascular Embolization by Transcatheter Delivery of Particles: Past, Present, and Future
title_short Endovascular Embolization by Transcatheter Delivery of Particles: Past, Present, and Future
title_sort endovascular embolization by transcatheter delivery of particles past present and future
topic biomaterials
biomedical devices
cardiovascular devices
drug delivery systems
microspheres
microfluidics
url http://www.mdpi.com/2079-4983/8/2/12
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