Development of a Genome-Scale Metabolic Model and Phenome Analysis of the Probiotic <i>Escherichia coli</i> Strain Nissle 1917

Development of a Genome-Scale Metabolic Model and Phenome Analysis of the Probiotic <i>Escherichia coli</i> Strain Nissle 1917

<i>Escherichia coli</i> Nissle 1917 (EcN) is an intestinal probiotic that is effective for the treatment of intestinal disorders, such as inflammatory bowel disease and ulcerative colitis. EcN is a representative Gram-negative probiotic in biomedical research and is an intensively studie...

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Bibliographic Details
Main Authors: Dohyeon Kim, Youngshin Kim, Sung Ho Yoon
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Escherichia coli</i> Nissle 1917
probiotics
metabolic network model
phenome analysis
flux balance analysis
Online Access:https://www.mdpi.com/1422-0067/22/4/2122

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