Mutational analysis of reverse transcriptase and surface proteins of patients with partial virological response during mono and combination antiviral therapies in genotype D chronic hepatitis B

Mutational analysis of reverse transcriptase and surface proteins of patients with partial virological response during mono and combination antiviral therapies in genotype D chronic hepatitis B

Introduction: The mutational pattern of chronic Hepatitis B virus (HBV) is unclear in patients who show incomplete response to antiviral therapy. The aims of this study were 1) to determine the benefit of combination therapy with adefovir dipivoxil (ADV) and Lamivudine (LAM) versus ADV or LAM alon...

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Bibliographic Details
Main Authors: Mostafa Mahabadi, Seyed Moayed Alavian, Mehdi Norouzi, Hossein Keyvani, Mahmood Mahmoudi, Seyed Mohammad Jazayeri
Format: Article
Language:English
Published: Electronic Physician 2016-06-01
Series:Electronic Physician
Subjects:
nucleoside analogues (NA)
partial response
drug resistant variants
hepatitis
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965195/

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