Regulation of Secondary Metabolism in the <i>Penicillium</i> Genus
<i>Penicillium</i>, one of the most common fungi occurring in a diverse range of habitats, has a worldwide distribution and a large economic impact on human health. Hundreds of the species belonging to this genus cause disastrous decay in food crops and are able to produce a varied range...
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MDPI AG
2020-12-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/21/24/9462 |
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| author | Christelle El Hajj Assaf Chrystian Zetina-Serrano Nadia Tahtah André El Khoury Ali Atoui Isabelle P. Oswald Olivier Puel Sophie Lorber |
| author_facet | Christelle El Hajj Assaf Chrystian Zetina-Serrano Nadia Tahtah André El Khoury Ali Atoui Isabelle P. Oswald Olivier Puel Sophie Lorber |
| author_sort | Christelle El Hajj Assaf |
| collection | DOAJ |
| description | <i>Penicillium</i>, one of the most common fungi occurring in a diverse range of habitats, has a worldwide distribution and a large economic impact on human health. Hundreds of the species belonging to this genus cause disastrous decay in food crops and are able to produce a varied range of secondary metabolites, from which we can distinguish harmful mycotoxins. Some <i>Penicillium</i> species are considered to be important producers of patulin and ochratoxin A, two well-known mycotoxins. The production of these mycotoxins and other secondary metabolites is controlled and regulated by different mechanisms. The aim of this review is to highlight the different levels of regulation of secondary metabolites in the <i>Penicillium</i> genus. |
| first_indexed | 2024-03-10T14:08:15Z |
| format | Article |
| id | doaj.art-d9e6c7e66fbe4c88b5256fbafc8c3fd4 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T14:08:15Z |
| publishDate | 2020-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-d9e6c7e66fbe4c88b5256fbafc8c3fd42023-11-21T00:31:07ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672020-12-012124946210.3390/ijms21249462Regulation of Secondary Metabolism in the <i>Penicillium</i> GenusChristelle El Hajj Assaf0Chrystian Zetina-Serrano1Nadia Tahtah2André El Khoury3Ali Atoui4Isabelle P. Oswald5Olivier Puel6Sophie Lorber7Toxalim (Research Centre in Food Toxicology), Université de Toulouse, INRAE, ENVT, INP-Purpan, UPS, 31027 Toulouse, FranceToxalim (Research Centre in Food Toxicology), Université de Toulouse, INRAE, ENVT, INP-Purpan, UPS, 31027 Toulouse, FranceToxalim (Research Centre in Food Toxicology), Université de Toulouse, INRAE, ENVT, INP-Purpan, UPS, 31027 Toulouse, FranceCentre D’analyse et de Recherche, Unité de Recherche Technologies et Valorisations Agro-Alimentaires, Faculté des Sciences, Université Saint-Joseph, P.O. Box 17-5208, Mar Mikhael, Beirut 1104, LebanonLaboratory of Microbiology, Department of Life and Earth Sciences, Faculty of Sciences I, Lebanese University, Hadath Campus, P.O. Box 5, Beirut 1104, LebanonToxalim (Research Centre in Food Toxicology), Université de Toulouse, INRAE, ENVT, INP-Purpan, UPS, 31027 Toulouse, FranceToxalim (Research Centre in Food Toxicology), Université de Toulouse, INRAE, ENVT, INP-Purpan, UPS, 31027 Toulouse, FranceToxalim (Research Centre in Food Toxicology), Université de Toulouse, INRAE, ENVT, INP-Purpan, UPS, 31027 Toulouse, France<i>Penicillium</i>, one of the most common fungi occurring in a diverse range of habitats, has a worldwide distribution and a large economic impact on human health. Hundreds of the species belonging to this genus cause disastrous decay in food crops and are able to produce a varied range of secondary metabolites, from which we can distinguish harmful mycotoxins. Some <i>Penicillium</i> species are considered to be important producers of patulin and ochratoxin A, two well-known mycotoxins. The production of these mycotoxins and other secondary metabolites is controlled and regulated by different mechanisms. The aim of this review is to highlight the different levels of regulation of secondary metabolites in the <i>Penicillium</i> genus.https://www.mdpi.com/1422-0067/21/24/9462<i>Penicillium</i>secondary metabolismregulationvirulencecontrol of gene expressiontranscription factors |
| spellingShingle | Christelle El Hajj Assaf Chrystian Zetina-Serrano Nadia Tahtah André El Khoury Ali Atoui Isabelle P. Oswald Olivier Puel Sophie Lorber Regulation of Secondary Metabolism in the <i>Penicillium</i> Genus International Journal of Molecular Sciences <i>Penicillium</i> secondary metabolism regulation virulence control of gene expression transcription factors |
| title | Regulation of Secondary Metabolism in the <i>Penicillium</i> Genus |
| title_full | Regulation of Secondary Metabolism in the <i>Penicillium</i> Genus |
| title_fullStr | Regulation of Secondary Metabolism in the <i>Penicillium</i> Genus |
| title_full_unstemmed | Regulation of Secondary Metabolism in the <i>Penicillium</i> Genus |
| title_short | Regulation of Secondary Metabolism in the <i>Penicillium</i> Genus |
| title_sort | regulation of secondary metabolism in the i penicillium i genus |
| topic | <i>Penicillium</i> secondary metabolism regulation virulence control of gene expression transcription factors |
| url | https://www.mdpi.com/1422-0067/21/24/9462 |
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