PEGylated exenatide injection (PB-119) improves beta-cell function and insulin resistance in treatment-naïve type 2 diabetes mellitus patients

PEGylated exenatide injection (PB-119) improves beta-cell function and insulin resistance in treatment-naïve type 2 diabetes mellitus patients

Objective: PB-119, a PEGylated exenatide injection, is a once-weekly glucagon-like peptide-1 receptor agonist. In the present study, we aimed to evaluate the effects of PB-119 on insulin resistance and beta-cell function in Chinese patients with type 2 diabetes mellitus (T2DM) to uncover its antidia...

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Bibliographic Details
Main Authors: Xu Liu, Ling Song, Yuanhui Zhang, Haiyan Li, Cheng Cui, Dongyang Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Pharmacology
Subjects:
PB-119
beta-cell function
insulin resistance
oral minimal model
type 2 diabetes
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1088670/full

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