Prevalence of dyslipidemia, atherogenic and cardiovascular risk in overweight and obese adolescents
Abstract Objective: To analyze the lipid profile and cardiovascular risk of overweight and obese adolescents and correlate the findings with anthropometric measurements. Methods: This is a cross-sectional study on overweight and obese adolescents of both sexes (aged 14 to 18 years old). The collec...
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| Format: | Article |
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Sociedade de Pediatria de São Paulo
2023-03-01
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| Series: | Revista Paulista de Pediatria |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822023000100429&lng=en&tlng=en |
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| author | Clara dos Santos de Andrades Victória Volkweis Poletti Vera Elizabeth Closs Andreia da Silva Gustavo Margareth da Silva Oliveira Márcio Vinícius Fagundes Donadio Ana Maria Pandolfo Feoli |
| author_facet | Clara dos Santos de Andrades Victória Volkweis Poletti Vera Elizabeth Closs Andreia da Silva Gustavo Margareth da Silva Oliveira Márcio Vinícius Fagundes Donadio Ana Maria Pandolfo Feoli |
| author_sort | Clara dos Santos de Andrades |
| collection | DOAJ |
| description | Abstract Objective: To analyze the lipid profile and cardiovascular risk of overweight and obese adolescents and correlate the findings with anthropometric measurements. Methods: This is a cross-sectional study on overweight and obese adolescents of both sexes (aged 14 to 18 years old). The collected variables were sex, weight, height, age, total cholesterol, triglycerides, High-density lipoprotein (HDL) and low-density lipoprotein (LDL). The Atherogenic Index of Plasma and Castelli Risk Indices I and II were calculated. These indices were classified into cutoff points to stratify cardiovascular risk. The anthropometric profile was evaluated by Z score according to Body Mass Index for age. Significance level was considered as p≤0.05. Results: A total of 146 adolescents participated in the study; the mean age was 16.4±1.1 years and most of them were girls (74.7%) and obese (52.7%). The prevalent dyslipidemias were high triglycerides (47.9%), LDL (26.7%), total cholesterol (37.7%), and low HDL (46.6%). Most adolescents presented increased atherogenic risk according to the Atherogenic Index of Plasma (55.5%); 15.1% presented high cardiovascular risk according to Castelli Risk Index I; and 13.7%, according to Castelli Risk Index II. Boys presented higher values of anthropometric measurements and Castelli Risk Indices I and II in relation to girls — who, conversely, presented higher values of HDL. There was a positive correlation of the Z score with Atherogenic Index of Plasma and a negative correlation with HDL. Conclusions: The adolescents of the study presented high prevalence of cardiovascular and atherogenic risk according to the evaluated indices. In addition, the increased cardiovascular risk was correlated with higher Body Mass Index. |
| first_indexed | 2024-04-10T00:40:03Z |
| format | Article |
| id | doaj.art-d9ee0bb06def49f98a1194d25468629c |
| institution | Directory Open Access Journal |
| issn | 1984-0462 |
| language | English |
| last_indexed | 2024-04-10T00:40:03Z |
| publishDate | 2023-03-01 |
| publisher | Sociedade de Pediatria de São Paulo |
| record_format | Article |
| series | Revista Paulista de Pediatria |
| spelling | doaj.art-d9ee0bb06def49f98a1194d25468629c2023-03-14T07:33:17ZengSociedade de Pediatria de São PauloRevista Paulista de Pediatria1984-04622023-03-014110.1590/1984-0462/2023/41/2021312Prevalence of dyslipidemia, atherogenic and cardiovascular risk in overweight and obese adolescentsClara dos Santos de Andradeshttps://orcid.org/0000-0002-5954-0496Victória Volkweis Polettihttps://orcid.org/0000-0002-5337-8002Vera Elizabeth Closshttps://orcid.org/0000-0002-7602-3984Andreia da Silva Gustavohttps://orcid.org/0000-0002-1128-2192Margareth da Silva Oliveirahttps://orcid.org/0000-0002-6490-5170Márcio Vinícius Fagundes Donadiohttps://orcid.org/0000-0001-8836-9109Ana Maria Pandolfo Feolihttps://orcid.org/0000-0001-7685-8431Abstract Objective: To analyze the lipid profile and cardiovascular risk of overweight and obese adolescents and correlate the findings with anthropometric measurements. Methods: This is a cross-sectional study on overweight and obese adolescents of both sexes (aged 14 to 18 years old). The collected variables were sex, weight, height, age, total cholesterol, triglycerides, High-density lipoprotein (HDL) and low-density lipoprotein (LDL). The Atherogenic Index of Plasma and Castelli Risk Indices I and II were calculated. These indices were classified into cutoff points to stratify cardiovascular risk. The anthropometric profile was evaluated by Z score according to Body Mass Index for age. Significance level was considered as p≤0.05. Results: A total of 146 adolescents participated in the study; the mean age was 16.4±1.1 years and most of them were girls (74.7%) and obese (52.7%). The prevalent dyslipidemias were high triglycerides (47.9%), LDL (26.7%), total cholesterol (37.7%), and low HDL (46.6%). Most adolescents presented increased atherogenic risk according to the Atherogenic Index of Plasma (55.5%); 15.1% presented high cardiovascular risk according to Castelli Risk Index I; and 13.7%, according to Castelli Risk Index II. Boys presented higher values of anthropometric measurements and Castelli Risk Indices I and II in relation to girls — who, conversely, presented higher values of HDL. There was a positive correlation of the Z score with Atherogenic Index of Plasma and a negative correlation with HDL. Conclusions: The adolescents of the study presented high prevalence of cardiovascular and atherogenic risk according to the evaluated indices. In addition, the increased cardiovascular risk was correlated with higher Body Mass Index.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822023000100429&lng=en&tlng=enAdolescentObesityCardiovascular diseasesAtherosclerosisLipid metabolism disordersBody mass index |
| spellingShingle | Clara dos Santos de Andrades Victória Volkweis Poletti Vera Elizabeth Closs Andreia da Silva Gustavo Margareth da Silva Oliveira Márcio Vinícius Fagundes Donadio Ana Maria Pandolfo Feoli Prevalence of dyslipidemia, atherogenic and cardiovascular risk in overweight and obese adolescents Revista Paulista de Pediatria Adolescent Obesity Cardiovascular diseases Atherosclerosis Lipid metabolism disorders Body mass index |
| title | Prevalence of dyslipidemia, atherogenic and cardiovascular risk in overweight and obese adolescents |
| title_full | Prevalence of dyslipidemia, atherogenic and cardiovascular risk in overweight and obese adolescents |
| title_fullStr | Prevalence of dyslipidemia, atherogenic and cardiovascular risk in overweight and obese adolescents |
| title_full_unstemmed | Prevalence of dyslipidemia, atherogenic and cardiovascular risk in overweight and obese adolescents |
| title_short | Prevalence of dyslipidemia, atherogenic and cardiovascular risk in overweight and obese adolescents |
| title_sort | prevalence of dyslipidemia atherogenic and cardiovascular risk in overweight and obese adolescents |
| topic | Adolescent Obesity Cardiovascular diseases Atherosclerosis Lipid metabolism disorders Body mass index |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822023000100429&lng=en&tlng=en |
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