Phospholipase Cε Modulates Rap1 Activity and the Endothelial Barrier.

The phosphoinositide-specific phospholipase C, PLCε, is a unique signaling protein with known roles in regulating cardiac myocyte growth, astrocyte inflammatory signaling, and tumor formation. PLCε is also expressed in endothelial cells, however its role in endothelial regulation is not fully establ...

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Bibliographic Details
Main Authors: Peter V DiStefano, Alan V Smrcka, Angela J Glading
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5017709?pdf=render