Association between family functioning and psychotic transition in ultra-high risk adolescents and young adults
BackgroundPsychotic transition (PT) is a crucial stage in schizophrenia. The Comprehensive Assessment of At-Risk Mental States (CAARMS) scale can be used to identify individuals at ultra-high risk (UHR) for psychosis and to evaluate their risk of PT. Many environmental and genetic factors have been...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-06-01
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| Series: | Frontiers in Psychiatry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1177311/full |
| _version_ | 1827919942650953728 |
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| author | Vladimir Adrien Vladimir Adrien Justine Liewig Thomas Diot Florian Ferreri Florian Ferreri Stephane Mouchabac Stephane Mouchabac Caroline Dubertret Julie Bourgin |
| author_facet | Vladimir Adrien Vladimir Adrien Justine Liewig Thomas Diot Florian Ferreri Florian Ferreri Stephane Mouchabac Stephane Mouchabac Caroline Dubertret Julie Bourgin |
| author_sort | Vladimir Adrien |
| collection | DOAJ |
| description | BackgroundPsychotic transition (PT) is a crucial stage in schizophrenia. The Comprehensive Assessment of At-Risk Mental States (CAARMS) scale can be used to identify individuals at ultra-high risk (UHR) for psychosis and to evaluate their risk of PT. Many environmental and genetic factors have been identified as contributing to the development and decompensation of schizophrenia. This study aimed to determine if the quality of family functioning is associated with PT risk in UHR individuals aged between 11 and 25 years after 1 year of follow-up.MethodsFrom January to November 2017, 45 patients aged 12 to 25 consulting for psychiatric reasons were included. Twenty-six were classified as UHR of PT at the CAARMS. Family functioning was assessed by the Family Assessment Device—Global Functioning (FAD-GF). Thirty-seven of these patients (30% men, mean age 16 ± 2.5) were reassessed at 8–14 months of recruitment. Survival analysis was used to examine the impact of family functioning on PT risk.ResultsA total of 40% of UHR patients were classified as psychotic at reassessment. Survival analysis showed that better family functioning is a significant protective factor for PT in this population.DiscussionThis result suggests that the global family functioning has an impact at 1 year on the risk of PT in the population of adolescents and young adults who consult the hospital for psychiatric reasons. A family intervention may be effective in reducing PT risk in this population and should be considered as a potential therapeutic option. |
| first_indexed | 2024-03-13T04:05:42Z |
| format | Article |
| id | doaj.art-d9f19723a8db4eefb499fcf3ab852e17 |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-03-13T04:05:42Z |
| publishDate | 2023-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-d9f19723a8db4eefb499fcf3ab852e172023-06-21T08:10:40ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402023-06-011410.3389/fpsyt.2023.11773111177311Association between family functioning and psychotic transition in ultra-high risk adolescents and young adultsVladimir Adrien0Vladimir Adrien1Justine Liewig2Thomas Diot3Florian Ferreri4Florian Ferreri5Stephane Mouchabac6Stephane Mouchabac7Caroline Dubertret8Julie Bourgin9AP-HP, Department of Psychiatry, Saint-Antoine Hospital, Sorbonne Université, Paris, FranceInfrastructure for Clinical Research in Neuroscience (iCRIN), Paris Brain Institute, Sorbonne Université, INSERM, CNRS, Paris, FranceDepartment of Child and Adolescent Psychiatry, Nord-Essonne Hospital, Bures-sur-Yvette, FranceAP-HP, Department of Psychiatry, Saint-Antoine Hospital, Sorbonne Université, Paris, FranceAP-HP, Department of Psychiatry, Saint-Antoine Hospital, Sorbonne Université, Paris, FranceInfrastructure for Clinical Research in Neuroscience (iCRIN), Paris Brain Institute, Sorbonne Université, INSERM, CNRS, Paris, FranceAP-HP, Department of Psychiatry, Saint-Antoine Hospital, Sorbonne Université, Paris, FranceInfrastructure for Clinical Research in Neuroscience (iCRIN), Paris Brain Institute, Sorbonne Université, INSERM, CNRS, Paris, FranceAP-HP, Department of Psychiatry, Louis Mourier Hospital, Université Paris Cité, Faculté de Médecine, Colombes, FranceDepartment of Child and Adolescent Psychiatry, Nord-Essonne Hospital, Bures-sur-Yvette, FranceBackgroundPsychotic transition (PT) is a crucial stage in schizophrenia. The Comprehensive Assessment of At-Risk Mental States (CAARMS) scale can be used to identify individuals at ultra-high risk (UHR) for psychosis and to evaluate their risk of PT. Many environmental and genetic factors have been identified as contributing to the development and decompensation of schizophrenia. This study aimed to determine if the quality of family functioning is associated with PT risk in UHR individuals aged between 11 and 25 years after 1 year of follow-up.MethodsFrom January to November 2017, 45 patients aged 12 to 25 consulting for psychiatric reasons were included. Twenty-six were classified as UHR of PT at the CAARMS. Family functioning was assessed by the Family Assessment Device—Global Functioning (FAD-GF). Thirty-seven of these patients (30% men, mean age 16 ± 2.5) were reassessed at 8–14 months of recruitment. Survival analysis was used to examine the impact of family functioning on PT risk.ResultsA total of 40% of UHR patients were classified as psychotic at reassessment. Survival analysis showed that better family functioning is a significant protective factor for PT in this population.DiscussionThis result suggests that the global family functioning has an impact at 1 year on the risk of PT in the population of adolescents and young adults who consult the hospital for psychiatric reasons. A family intervention may be effective in reducing PT risk in this population and should be considered as a potential therapeutic option.https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1177311/fullpsychotic transitionfamily functioningenvironmentadolescentFAD-60 |
| spellingShingle | Vladimir Adrien Vladimir Adrien Justine Liewig Thomas Diot Florian Ferreri Florian Ferreri Stephane Mouchabac Stephane Mouchabac Caroline Dubertret Julie Bourgin Association between family functioning and psychotic transition in ultra-high risk adolescents and young adults Frontiers in Psychiatry psychotic transition family functioning environment adolescent FAD-60 |
| title | Association between family functioning and psychotic transition in ultra-high risk adolescents and young adults |
| title_full | Association between family functioning and psychotic transition in ultra-high risk adolescents and young adults |
| title_fullStr | Association between family functioning and psychotic transition in ultra-high risk adolescents and young adults |
| title_full_unstemmed | Association between family functioning and psychotic transition in ultra-high risk adolescents and young adults |
| title_short | Association between family functioning and psychotic transition in ultra-high risk adolescents and young adults |
| title_sort | association between family functioning and psychotic transition in ultra high risk adolescents and young adults |
| topic | psychotic transition family functioning environment adolescent FAD-60 |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1177311/full |
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