Towards Accurate and Precise Image-Guided Radiotherapy: Clinical Applications of the MR-Linac
Advances in image-guided radiotherapy have brought about improved oncologic outcomes and reduced toxicity. The next generation of image guidance in the form of magnetic resonance imaging (MRI) will improve visualization of tumors and make radiation treatment adaptation possible. In this review, we d...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-07-01
|
| Series: | Journal of Clinical Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0383/11/14/4044 |
| _version_ | 1797433494300786688 |
|---|---|
| author | James W. Randall Nikhil Rammohan Indra J. Das Poonam Yadav |
| author_facet | James W. Randall Nikhil Rammohan Indra J. Das Poonam Yadav |
| author_sort | James W. Randall |
| collection | DOAJ |
| description | Advances in image-guided radiotherapy have brought about improved oncologic outcomes and reduced toxicity. The next generation of image guidance in the form of magnetic resonance imaging (MRI) will improve visualization of tumors and make radiation treatment adaptation possible. In this review, we discuss the role that MRI plays in radiotherapy, with a focus on the integration of MRI with the linear accelerator. The MR linear accelerator (MR-Linac) will provide real-time imaging, help assess motion management, and provide online adaptive therapy. Potential advantages and the current state of these MR-Linacs are highlighted, with a discussion of six different clinical scenarios, leading into a discussion on the future role of these machines in clinical workflows. |
| first_indexed | 2024-03-09T10:17:47Z |
| format | Article |
| id | doaj.art-d9f27ccc0e6341ce8043c39278f90b9f |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T10:17:47Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-d9f27ccc0e6341ce8043c39278f90b9f2023-12-01T22:18:06ZengMDPI AGJournal of Clinical Medicine2077-03832022-07-011114404410.3390/jcm11144044Towards Accurate and Precise Image-Guided Radiotherapy: Clinical Applications of the MR-LinacJames W. Randall0Nikhil Rammohan1Indra J. Das2Poonam Yadav3Northwestern Medicine, Department of Radiation Oncology, Chicago, IL 60611, USANorthwestern Medicine, Department of Radiation Oncology, Chicago, IL 60611, USANorthwestern Medicine, Department of Radiation Oncology, Chicago, IL 60611, USANorthwestern Medicine, Department of Radiation Oncology, Chicago, IL 60611, USAAdvances in image-guided radiotherapy have brought about improved oncologic outcomes and reduced toxicity. The next generation of image guidance in the form of magnetic resonance imaging (MRI) will improve visualization of tumors and make radiation treatment adaptation possible. In this review, we discuss the role that MRI plays in radiotherapy, with a focus on the integration of MRI with the linear accelerator. The MR linear accelerator (MR-Linac) will provide real-time imaging, help assess motion management, and provide online adaptive therapy. Potential advantages and the current state of these MR-Linacs are highlighted, with a discussion of six different clinical scenarios, leading into a discussion on the future role of these machines in clinical workflows.https://www.mdpi.com/2077-0383/11/14/4044magnetic resonancelinear acceleratorMRgRTradiotherapyimage-guided radiotherapyIGRT |
| spellingShingle | James W. Randall Nikhil Rammohan Indra J. Das Poonam Yadav Towards Accurate and Precise Image-Guided Radiotherapy: Clinical Applications of the MR-Linac Journal of Clinical Medicine magnetic resonance linear accelerator MRgRT radiotherapy image-guided radiotherapy IGRT |
| title | Towards Accurate and Precise Image-Guided Radiotherapy: Clinical Applications of the MR-Linac |
| title_full | Towards Accurate and Precise Image-Guided Radiotherapy: Clinical Applications of the MR-Linac |
| title_fullStr | Towards Accurate and Precise Image-Guided Radiotherapy: Clinical Applications of the MR-Linac |
| title_full_unstemmed | Towards Accurate and Precise Image-Guided Radiotherapy: Clinical Applications of the MR-Linac |
| title_short | Towards Accurate and Precise Image-Guided Radiotherapy: Clinical Applications of the MR-Linac |
| title_sort | towards accurate and precise image guided radiotherapy clinical applications of the mr linac |
| topic | magnetic resonance linear accelerator MRgRT radiotherapy image-guided radiotherapy IGRT |
| url | https://www.mdpi.com/2077-0383/11/14/4044 |
| work_keys_str_mv | AT jameswrandall towardsaccurateandpreciseimageguidedradiotherapyclinicalapplicationsofthemrlinac AT nikhilrammohan towardsaccurateandpreciseimageguidedradiotherapyclinicalapplicationsofthemrlinac AT indrajdas towardsaccurateandpreciseimageguidedradiotherapyclinicalapplicationsofthemrlinac AT poonamyadav towardsaccurateandpreciseimageguidedradiotherapyclinicalapplicationsofthemrlinac |