Poorly differentiated synovial sarcoma is associated with high expression of enhancer of zeste homologue 2 (EZH2)

Poorly differentiated synovial sarcoma is associated with high expression of enhancer of zeste homologue 2 (EZH2)

<p>Abstract</p> <p>Background</p> <p>Enhancer of zeste homologue 2 (EZH2) is a polycomb group (PcG) family protein. Acting as a histone methyltransferase it plays crucial roles in maintaining epigenetic stem cell signature, while its deregulation leads to tumor developm...

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Bibliographic Details
Main Authors: Changchien Yi-Che, Tátrai Péter, Papp Gergő, Sápi Johanna, Fónyad László, Szendrői Miklós, Pápai Zsuzsanna, Sápi Zoltán
Format: Article
Language:English
Published: BMC 2012-10-01
Series:Journal of Translational Medicine
Subjects:
Synovial sarcoma
EZH2
Polycomb group
Histone methyltransferase
H3K27me3
Online Access:http://www.translational-medicine.com/content/10/1/216

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