Comparison of Antigenemia and Quantitative DNA Assay in Cytomegalovirus Disease
It was aimed to compare the results of the antigenemia test (Cinakit, Biosoft-Argene, Fransa) and the quantitative CMV DNA polymerase chain reaction test (Cobas Amplicor CMV Monitor Test, Roche Diagnostics, ABD) which are used in the diagnosis of CMV disease. Thirty leukocyte and plasma samples of 1...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Bilimsel Tip Yayinevi
2002-12-01
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| Series: | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
| Subjects: | |
| Online Access: | http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2002-7-4-241-245.pdf |
| _version_ | 1797906059988303872 |
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| author | Ayşın ZEYTİNOĞLU Selda ERENSOY Servet GÖKSEL Hüseyin TÖZ Nur YAPAR Altınay BİLGİÇ |
| author_facet | Ayşın ZEYTİNOĞLU Selda ERENSOY Servet GÖKSEL Hüseyin TÖZ Nur YAPAR Altınay BİLGİÇ |
| author_sort | Ayşın ZEYTİNOĞLU |
| collection | DOAJ |
| description | It was aimed to compare the results of the antigenemia test (Cinakit, Biosoft-Argene, Fransa) and the quantitative CMV DNA polymerase chain reaction test (Cobas Amplicor CMV Monitor Test, Roche Diagnostics, ABD) which are used in the diagnosis of CMV disease. Thirty leukocyte and plasma samples of 11 patients who admitted to the laboratory for antigenemia assay with clinical suspicion of CMV disease were included in the study. There was a mild correlation between antigenemia assay and leukocyte/plasma DNA results while this correlation was stronger between leukocyte and plasma DNA results that were obtained with the same system. As a conclusion, all three assays can be used in the diagnosis of CMV disease but at patient follow up, same test and clinical sample should be chosen. |
| first_indexed | 2024-04-10T10:15:02Z |
| format | Article |
| id | doaj.art-d9f946e21f824a3abaf81e6bd737f641 |
| institution | Directory Open Access Journal |
| issn | 1300-932X 1300-932X |
| language | English |
| last_indexed | 2024-04-10T10:15:02Z |
| publishDate | 2002-12-01 |
| publisher | Bilimsel Tip Yayinevi |
| record_format | Article |
| series | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
| spelling | doaj.art-d9f946e21f824a3abaf81e6bd737f6412023-02-15T16:21:56ZengBilimsel Tip YayineviFlora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi1300-932X1300-932X2002-12-0174241245Comparison of Antigenemia and Quantitative DNA Assay in Cytomegalovirus DiseaseAyşın ZEYTİNOĞLU0Selda ERENSOY1Servet GÖKSEL2Hüseyin TÖZ3Nur YAPAR4Altınay BİLGİÇ5Ege Üniversitesi Tıp Fakültesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dalı,Ege Üniversitesi Tıp Fakültesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dalı,Ege Üniversitesi Tıp Fakültesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dalı,Ege Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Nefroloji Bilim Dalı,Dokuz Eylül Üniversitesi Tıp Fakültesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, İZMİREge Üniversitesi Tıp Fakültesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dalı,It was aimed to compare the results of the antigenemia test (Cinakit, Biosoft-Argene, Fransa) and the quantitative CMV DNA polymerase chain reaction test (Cobas Amplicor CMV Monitor Test, Roche Diagnostics, ABD) which are used in the diagnosis of CMV disease. Thirty leukocyte and plasma samples of 11 patients who admitted to the laboratory for antigenemia assay with clinical suspicion of CMV disease were included in the study. There was a mild correlation between antigenemia assay and leukocyte/plasma DNA results while this correlation was stronger between leukocyte and plasma DNA results that were obtained with the same system. As a conclusion, all three assays can be used in the diagnosis of CMV disease but at patient follow up, same test and clinical sample should be chosen.http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2002-7-4-241-245.pdfCMV antigenemia assaypp65 antigenemia assayQuantitative CMV DNA PCR |
| spellingShingle | Ayşın ZEYTİNOĞLU Selda ERENSOY Servet GÖKSEL Hüseyin TÖZ Nur YAPAR Altınay BİLGİÇ Comparison of Antigenemia and Quantitative DNA Assay in Cytomegalovirus Disease Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi CMV antigenemia assay pp65 antigenemia assay Quantitative CMV DNA PCR |
| title | Comparison of Antigenemia and Quantitative DNA Assay in Cytomegalovirus Disease |
| title_full | Comparison of Antigenemia and Quantitative DNA Assay in Cytomegalovirus Disease |
| title_fullStr | Comparison of Antigenemia and Quantitative DNA Assay in Cytomegalovirus Disease |
| title_full_unstemmed | Comparison of Antigenemia and Quantitative DNA Assay in Cytomegalovirus Disease |
| title_short | Comparison of Antigenemia and Quantitative DNA Assay in Cytomegalovirus Disease |
| title_sort | comparison of antigenemia and quantitative dna assay in cytomegalovirus disease |
| topic | CMV antigenemia assay pp65 antigenemia assay Quantitative CMV DNA PCR |
| url | http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2002-7-4-241-245.pdf |
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