Bimodal expression of RHOH during myelomonocytic differentiation: Implications for the expansion of AML differentiation therapy

Bimodal expression of RHOH during myelomonocytic differentiation: Implications for the expansion of AML differentiation therapy

Abstract RhoH is an unusual member of the Rho family of small GTP‐binding proteins in that it lacks GTPase activity. Since the RhoH protein is constantly bound by GTP, it is constitutively active and controlled predominantly by changes in quantitative expression. Abnormal levels of RHOH gene transcr...

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Bibliographic Details
Main Authors: Sylvie Galiègue‐Zouitina, Qiangwei Fu, Céline Carton‐Latreche, Nicolas Poret, Meyling Cheok, Frédéric Leprêtre, Martin Figeac, Bruno Quesnel, Hassiba El Bouazzati, Carl S Shelley
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:eJHaem
Subjects:
AML
differentiation therapy
myeloid differentiation
RHOH
Online Access:https://doi.org/10.1002/jha2.128

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