Analysis of Risk Factors for in‐hospital Death in Elderly Patients with TEXAS Stage 3 and 4 Diabetic Foot Ulcers after Tibial Transverse Translation: A Case–Control Study

Objective Chinese physicians developed the Tibial Transverse Transport (TTT) technique to treat diabetic foot ulcers with more than 90% effective rate. But this method still could not avoid the in‐hospital death of patients. This study adopted a case‐control study to explore the risk factors of in‐h...

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Main Authors: Xiaofang Ding, Yusong Yuan, Hailin Xu, Zhengwei Jing, Hao Lu, Yuanli Wang, Junlin Zhou
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Orthopaedic Surgery
Subjects:
Online Access:https://doi.org/10.1111/os.13908
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author Xiaofang Ding
Yusong Yuan
Hailin Xu
Zhengwei Jing
Hao Lu
Yuanli Wang
Junlin Zhou
author_facet Xiaofang Ding
Yusong Yuan
Hailin Xu
Zhengwei Jing
Hao Lu
Yuanli Wang
Junlin Zhou
author_sort Xiaofang Ding
collection DOAJ
description Objective Chinese physicians developed the Tibial Transverse Transport (TTT) technique to treat diabetic foot ulcers with more than 90% effective rate. But this method still could not avoid the in‐hospital death of patients. This study adopted a case‐control study to explore the risk factors of in‐hospital death in elderly patients with chronic ischemic diabetic foot after receiving TTT treatment. Methods A total of 54 patients were included in the study from January 1, 2017 to April 30, 2021, by being paired with the cases in case group with their demographic data and results of blood routine, liver and kidney function. There were nine patients in case group with six male and three male. Forty‐five patients were selected in control group according to gender and diabetes type with 30 male and 15 female. Single factor logics regression analysis was used to explore the risk factors and odd ratios (OR) of in‐hospital death in patients. The nomogram and decision curve analysis (DCA) had been done by R Studio software. Results The study found that age, course of diabetic foot, small dense low‐density Lipoprotein (smLDL), homocysteine (Hcy), superoxide dismutase (SOD), and prealbumin (PA) were risk factors for in‐hospital death of patients. The smLDL had the highest risk. The nomogram showed that PA accounted for the largest proportion in the death risk factors. The results of DCA proved that above six risk factors were the risk factors for patients with TEXAS Stage 3 and 4 diabetic foot ulcers. Conclusion In the future diagnosis and TTT treatment for diabetic foot ulcers, doctors need to pay close attention to age, course of diabetic foot, smLDL, Hcy, SOD, and PA.
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spelling doaj.art-d9fc8635acd943b285c43b239ee864542023-12-04T02:35:49ZengWileyOrthopaedic Surgery1757-78531757-78612023-12-0115123272327810.1111/os.13908Analysis of Risk Factors for in‐hospital Death in Elderly Patients with TEXAS Stage 3 and 4 Diabetic Foot Ulcers after Tibial Transverse Translation: A Case–Control StudyXiaofang Ding0Yusong Yuan1Hailin Xu2Zhengwei Jing3Hao Lu4Yuanli Wang5Junlin Zhou6Department of Orthopaedics, Beijing Chaoyang Hospital Capital Medical University Beijing ChinaDepartment of Orthopaedic Surgery China‐Japan Friendship Hospital Beijing ChinaDepartment of Trauma and Orthopaedics, Peking University People's Hospital Peking University Beijing ChinaDepartment of Health Policy and Management, School of Public Health Peking University Beijing ChinaDepartment of Trauma and Orthopaedics, Peking University People's Hospital Peking University Beijing ChinaBeijing Longfu Hospital Beijing ChinaDepartment of Orthopaedics, Beijing Chaoyang Hospital Capital Medical University Beijing ChinaObjective Chinese physicians developed the Tibial Transverse Transport (TTT) technique to treat diabetic foot ulcers with more than 90% effective rate. But this method still could not avoid the in‐hospital death of patients. This study adopted a case‐control study to explore the risk factors of in‐hospital death in elderly patients with chronic ischemic diabetic foot after receiving TTT treatment. Methods A total of 54 patients were included in the study from January 1, 2017 to April 30, 2021, by being paired with the cases in case group with their demographic data and results of blood routine, liver and kidney function. There were nine patients in case group with six male and three male. Forty‐five patients were selected in control group according to gender and diabetes type with 30 male and 15 female. Single factor logics regression analysis was used to explore the risk factors and odd ratios (OR) of in‐hospital death in patients. The nomogram and decision curve analysis (DCA) had been done by R Studio software. Results The study found that age, course of diabetic foot, small dense low‐density Lipoprotein (smLDL), homocysteine (Hcy), superoxide dismutase (SOD), and prealbumin (PA) were risk factors for in‐hospital death of patients. The smLDL had the highest risk. The nomogram showed that PA accounted for the largest proportion in the death risk factors. The results of DCA proved that above six risk factors were the risk factors for patients with TEXAS Stage 3 and 4 diabetic foot ulcers. Conclusion In the future diagnosis and TTT treatment for diabetic foot ulcers, doctors need to pay close attention to age, course of diabetic foot, smLDL, Hcy, SOD, and PA.https://doi.org/10.1111/os.13908Case Control StudyDeathDiabetic FootIn HospitalTibial transverse transport
spellingShingle Xiaofang Ding
Yusong Yuan
Hailin Xu
Zhengwei Jing
Hao Lu
Yuanli Wang
Junlin Zhou
Analysis of Risk Factors for in‐hospital Death in Elderly Patients with TEXAS Stage 3 and 4 Diabetic Foot Ulcers after Tibial Transverse Translation: A Case–Control Study
Orthopaedic Surgery
Case Control Study
Death
Diabetic Foot
In Hospital
Tibial transverse transport
title Analysis of Risk Factors for in‐hospital Death in Elderly Patients with TEXAS Stage 3 and 4 Diabetic Foot Ulcers after Tibial Transverse Translation: A Case–Control Study
title_full Analysis of Risk Factors for in‐hospital Death in Elderly Patients with TEXAS Stage 3 and 4 Diabetic Foot Ulcers after Tibial Transverse Translation: A Case–Control Study
title_fullStr Analysis of Risk Factors for in‐hospital Death in Elderly Patients with TEXAS Stage 3 and 4 Diabetic Foot Ulcers after Tibial Transverse Translation: A Case–Control Study
title_full_unstemmed Analysis of Risk Factors for in‐hospital Death in Elderly Patients with TEXAS Stage 3 and 4 Diabetic Foot Ulcers after Tibial Transverse Translation: A Case–Control Study
title_short Analysis of Risk Factors for in‐hospital Death in Elderly Patients with TEXAS Stage 3 and 4 Diabetic Foot Ulcers after Tibial Transverse Translation: A Case–Control Study
title_sort analysis of risk factors for in hospital death in elderly patients with texas stage 3 and 4 diabetic foot ulcers after tibial transverse translation a case control study
topic Case Control Study
Death
Diabetic Foot
In Hospital
Tibial transverse transport
url https://doi.org/10.1111/os.13908
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