PREVALENCE AND RISK FACTORS OF ACTIVE TUBERCULOSIS AMONG HIV- POSITIVE CLIENTS RECEIVING ANTIRETRO VIRAL THERAPY AT VILLA MARIA HOSPITAL, KALUNGU DISTRICT: A CROSS SECTIONAL DESCRIPTIVE STUDY.
Background With the introduction of antiretroviral therapy (ART), TB remains a leading Co-infection among people living with HIV while on ART, responsible for 30% of deaths among PLHIV in Uganda. This study was designed to determine the prevalence and risk factors leading to the development of ac...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Student's Journal of Health Research
2023-12-01
|
| Series: | Student's Journal of Health Research Africa |
| Subjects: | |
| Online Access: | https://sjhresearchafrica.org/index.php/public-html/article/view/678 |
| _version_ | 1797398932125384704 |
|---|---|
| author | SSENTEZA MATHIUS Jonathan Kazibwe Godfrey Mugisa |
| author_facet | SSENTEZA MATHIUS Jonathan Kazibwe Godfrey Mugisa |
| author_sort | SSENTEZA MATHIUS |
| collection | DOAJ |
| description |
Background
With the introduction of antiretroviral therapy (ART), TB remains a leading Co-infection among people living with HIV while on ART, responsible for 30% of deaths among PLHIV in Uganda. This study was designed to determine the prevalence and risk factors leading to the development of active tuberculosis among HIV-positive clients receiving ART from Villa Maria Hospital in Kalungu district.
Methodology
A cross-sectional descriptive study that employed qualitative data collection methods was conducted among 160 HIV-positive clients. Participants with TB symptoms were diagnosed with TB using smear microscopy (Zn), gene-expert, and urine TB lam and chest x-ray. Data was collected, and analyzed by Microsoft Excel 2013, and results were presented in tables & figures.
Results
Among the participants, 44.4% and 55.6% were male & female respectively with a median age of 45 years. 25 (15.6%) of the patients had developed active TB infection, which was independently associated majorly with advanced HIV disease & non-users of TPT. The use of IPT & good adherence to ART reduced the risk of developing TB by over 80%. 33.8% didn’t know how TB spreads, and coughing, and living with a TB patient were the most identified ways in which TB spreads, Lack of food & long distances to the health centers were the major hindrances to completing TB treatment. Pill burden & frequent movement to health centers were the major challenges faced during TB treatment.
Conclusions
HIV clients with cough, advanced HIV disease, and non-users of TPT had an increased risk of developing TB infection. However, the use of TPT and good adherence to ART reduced the risk of TB among HIV-infected patients. Therefore, early screening of TB among HIV patients with cough, and involvement of VHTs/CHWs and community-based organizations (CBOs) to increase the awareness and control measures of TB in the communities.
|
| first_indexed | 2024-03-09T01:32:41Z |
| format | Article |
| id | doaj.art-d9fd2507c6ed48dfb7435610c63f08da |
| institution | Directory Open Access Journal |
| issn | 2709-9997 |
| language | English |
| last_indexed | 2024-03-09T01:32:41Z |
| publishDate | 2023-12-01 |
| publisher | Student's Journal of Health Research |
| record_format | Article |
| series | Student's Journal of Health Research Africa |
| spelling | doaj.art-d9fd2507c6ed48dfb7435610c63f08da2023-12-09T08:28:52ZengStudent's Journal of Health ResearchStudent's Journal of Health Research Africa2709-99972023-12-0141210.51168/sjhrafrica.v4i12.678PREVALENCE AND RISK FACTORS OF ACTIVE TUBERCULOSIS AMONG HIV- POSITIVE CLIENTS RECEIVING ANTIRETRO VIRAL THERAPY AT VILLA MARIA HOSPITAL, KALUNGU DISTRICT: A CROSS SECTIONAL DESCRIPTIVE STUDY.SSENTEZA MATHIUS 0Jonathan Kazibwe1Godfrey Mugisa2Villa Maria Hospital AIDS Home Care Program, Masaka-Uganda.Faculty of Health Sciences, University of Kisubi, Entebbe-Uganda.Villa Maria Hospital AIDS Home Care Program, Masaka-Uganda. Background With the introduction of antiretroviral therapy (ART), TB remains a leading Co-infection among people living with HIV while on ART, responsible for 30% of deaths among PLHIV in Uganda. This study was designed to determine the prevalence and risk factors leading to the development of active tuberculosis among HIV-positive clients receiving ART from Villa Maria Hospital in Kalungu district. Methodology A cross-sectional descriptive study that employed qualitative data collection methods was conducted among 160 HIV-positive clients. Participants with TB symptoms were diagnosed with TB using smear microscopy (Zn), gene-expert, and urine TB lam and chest x-ray. Data was collected, and analyzed by Microsoft Excel 2013, and results were presented in tables & figures. Results Among the participants, 44.4% and 55.6% were male & female respectively with a median age of 45 years. 25 (15.6%) of the patients had developed active TB infection, which was independently associated majorly with advanced HIV disease & non-users of TPT. The use of IPT & good adherence to ART reduced the risk of developing TB by over 80%. 33.8% didn’t know how TB spreads, and coughing, and living with a TB patient were the most identified ways in which TB spreads, Lack of food & long distances to the health centers were the major hindrances to completing TB treatment. Pill burden & frequent movement to health centers were the major challenges faced during TB treatment. Conclusions HIV clients with cough, advanced HIV disease, and non-users of TPT had an increased risk of developing TB infection. However, the use of TPT and good adherence to ART reduced the risk of TB among HIV-infected patients. Therefore, early screening of TB among HIV patients with cough, and involvement of VHTs/CHWs and community-based organizations (CBOs) to increase the awareness and control measures of TB in the communities. https://sjhresearchafrica.org/index.php/public-html/article/view/678Mycobacterium TuberculosisTB LamPeople living with HIVTB preventive Therapy (TPT) |
| spellingShingle | SSENTEZA MATHIUS Jonathan Kazibwe Godfrey Mugisa PREVALENCE AND RISK FACTORS OF ACTIVE TUBERCULOSIS AMONG HIV- POSITIVE CLIENTS RECEIVING ANTIRETRO VIRAL THERAPY AT VILLA MARIA HOSPITAL, KALUNGU DISTRICT: A CROSS SECTIONAL DESCRIPTIVE STUDY. Student's Journal of Health Research Africa Mycobacterium Tuberculosis TB Lam People living with HIV TB preventive Therapy (TPT) |
| title | PREVALENCE AND RISK FACTORS OF ACTIVE TUBERCULOSIS AMONG HIV- POSITIVE CLIENTS RECEIVING ANTIRETRO VIRAL THERAPY AT VILLA MARIA HOSPITAL, KALUNGU DISTRICT: A CROSS SECTIONAL DESCRIPTIVE STUDY. |
| title_full | PREVALENCE AND RISK FACTORS OF ACTIVE TUBERCULOSIS AMONG HIV- POSITIVE CLIENTS RECEIVING ANTIRETRO VIRAL THERAPY AT VILLA MARIA HOSPITAL, KALUNGU DISTRICT: A CROSS SECTIONAL DESCRIPTIVE STUDY. |
| title_fullStr | PREVALENCE AND RISK FACTORS OF ACTIVE TUBERCULOSIS AMONG HIV- POSITIVE CLIENTS RECEIVING ANTIRETRO VIRAL THERAPY AT VILLA MARIA HOSPITAL, KALUNGU DISTRICT: A CROSS SECTIONAL DESCRIPTIVE STUDY. |
| title_full_unstemmed | PREVALENCE AND RISK FACTORS OF ACTIVE TUBERCULOSIS AMONG HIV- POSITIVE CLIENTS RECEIVING ANTIRETRO VIRAL THERAPY AT VILLA MARIA HOSPITAL, KALUNGU DISTRICT: A CROSS SECTIONAL DESCRIPTIVE STUDY. |
| title_short | PREVALENCE AND RISK FACTORS OF ACTIVE TUBERCULOSIS AMONG HIV- POSITIVE CLIENTS RECEIVING ANTIRETRO VIRAL THERAPY AT VILLA MARIA HOSPITAL, KALUNGU DISTRICT: A CROSS SECTIONAL DESCRIPTIVE STUDY. |
| title_sort | prevalence and risk factors of active tuberculosis among hiv positive clients receiving antiretro viral therapy at villa maria hospital kalungu district a cross sectional descriptive study |
| topic | Mycobacterium Tuberculosis TB Lam People living with HIV TB preventive Therapy (TPT) |
| url | https://sjhresearchafrica.org/index.php/public-html/article/view/678 |
| work_keys_str_mv | AT ssentezamathius prevalenceandriskfactorsofactivetuberculosisamonghivpositiveclientsreceivingantiretroviraltherapyatvillamariahospitalkalungudistrictacrosssectionaldescriptivestudy AT jonathankazibwe prevalenceandriskfactorsofactivetuberculosisamonghivpositiveclientsreceivingantiretroviraltherapyatvillamariahospitalkalungudistrictacrosssectionaldescriptivestudy AT godfreymugisa prevalenceandriskfactorsofactivetuberculosisamonghivpositiveclientsreceivingantiretroviraltherapyatvillamariahospitalkalungudistrictacrosssectionaldescriptivestudy |